Lisa Marie Simpson, voiced by Yeardley Smith, is Homer and Marge's oldest duaghter and the middle child on The Simpsons.  Lisa is very intelligent, plays the saxophone, is a vegetarian, Buddhist, and definitely a bit of a young political activist.  She's basically the complete opposite of her brother, Bart.

Lisa Simpson Quotes

Lincoln, Lincoln. I've been thinkin'. What the hell have you've been drinkin'? Is it water? Is it wine? Oh, my gosh. It's turpentine!

Bart & Lisa

Worker: We found this one swimming naked in the pool.
Lisa: I am the lizard queen!

The Simpsons Quotes

Homer: (Wearing glasses) The sum of the square roots of any two sides of an isosceles triangle is equal to the square root of the remaining side!
Man: (From inside a bathroom stall.) That's a right triangle, you idiot!
Homer: D'oh!

You know, you remind me of a poem I can't remember, and a song that may never have existed, and a place I'm not sure I've ever been to.

Grampa