Sheldon and Amy

Sheldon and Amy

Sheldon runs into a character played by Mayim Bialik on the 5/17/10 episode of The Big Bang Theory. Might she be the one for him?
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Big Bang Scene

Big Bang Scene

You gotta love this guest-starring appearance on The Big Bang Theory: that's former sitcom star Mayim Bialik!
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Mayim Bialik on The Big Bang Theory

Mayim Bialik on The Big Bang Theory

This is a scene from the 5/17/10 episode of The Big Bang Theory. Yes, that's Mayim Bialik guest-starring in the sitcom.
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Judy Greer on Big Bang Theory

Judy Greer on Big Bang Theory

Judy Greer guest starred on The Big Bang Theory as Dr. Plimpton, a famous physicist that Sheldon invites to spend the weekend at the place.
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Back from Disney Land

Back from Disney Land

Penny returns Sheldon to Leonard after their trip to Disney Land. The couple is sharing custody over the nerd.
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Leonard and Leslie

Leonard and Leslie

Sara Gilbert is seen here on The Big Bang Theory. She plays the character of Leslie.
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In Drag

In Drag

This is a photo from the episode "The Wheaton Recurrence." There's really not much to say about it, is there?
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Wil Wheaton Bowling

Wil Wheaton Bowling

A picture after Wil Wheaton just bowled as Sheldon prepares to counter.
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Penny and Leonard Bowling

Penny and Leonard Bowling

Penny and Leonard go bowling and Leoanrd sure does seem to be celebrating something.
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Wheaton Calls Out Sheldon

Wheaton Calls Out Sheldon

Wil Wheaton calls out Sheldon as the two of them meet in the bowling alley.
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The Wesley Crushers

The Wesley Crushers

Sheldon has a shirt made that says "The Wesley Crushers" for his bowl off with Wil Wheaton. Get it? No? Wheaton played Wesley on Star Trek.
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Sheldon Vs Wheaton

Sheldon Vs Wheaton

Sheldon goes up against Wil Wheaton in the ultimate bowl off between rivals.
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TBBT Quotes

Later, Losers!

Raj

Okay, please don't take this the wrong way, but I'd rather swim butt-naked across the Ganges with a paper cut on my nipple and die a slow agonizing death from a viral infection than work with you

Raj [to Sheldon]