Several couples connect as the episode opens.
Yasuda reveals that she and Helm are trying to repair their relationship.
Amelia is nervous when she finds Catherine exploring her lab. Catherine doesn't say what she saw, but Amelia suspects she knows about the Alzheimer's research Amelia and Meredith are doing.
Maggie is back in the hospital for the first time in a long time to see a patient. She runs into Winston, and their interaction is awkward.
Altman and Bailey discuss with Adams that the family of Sam Sutton is going to settle with the hospital, but that he is being advised to repeat his intern year.
Winston and Beltran work together on a teenager who needs a heart and lung transplant.
Maggie asks Adams to work with her on her patient. The patient is rejecting his transplanted organs and will need a new heart or he will die.
Amelia shows up in Boston at Meredith's house and brings all of the research with her to keep it hidden from Catherine.
Meredith and Amelia talk with Altman about their fears that Catherine is onto them.
Winston invites Maggie to scrub in on his transplant patient since she was a previous provider of his. The two manage to joke around with each other.
Altman recruits Millin and Blue to help with entering the Alzheimers data into the computer system.
Jo and Link argue about how to treat a patient.
Amelia worries that their research will invalidate all the work Derek ever did on the subject.
Ndugu and Beltran's transplant patient might be able to donate his rejected organs to Maggie's patient.
Altman confesses to Hunt about funding Meredith's research, and then Owen confesses that he went to Catherine to fund his idea for first aid training education.
The hand-me-down heart is damaged, but the doctors think they can repair it enough to give it to Maggie's patient.
Nick tells Meredith that he wants to marry her and that he's frustrated that she is risking her job and stability by going around Catherine.
Link went over Jo's head to Carina to discuss his concerns about her patient.
Meredith and Amelia realize that they were right about their hypothesis and that they may actually have the ability to prevent Alzheimer's. Amelia realizes the data is too important to avoid publishing.
Maggie offers Adams a job working for her in Chicago.
Maggie tries to kiss Winston but he dodges her kiss. He is finally ready to move on and gives her the signed divorce papers.
Adams tells Griffin that he's considering taking the job with Maggie.
Bailey says she feels confident that the interns have grown as much as she needed them to.
Yasuda breaks up with Helm in the middle of the E.R. She says her reasoning is based on the power dynamic since Helm is her boss.
Altman tells Catherine that she's funding Meredith's project. Catherine compliments her for being honest, but is obviously furious.
Jo and Link make up and decide to keep work and home separate.
Winston and Beltran bond over divorce and end up hooking up.
Meredith and Nick are at odds over the fact that she prioritizes work over him.
Catherine fires Teddy over the funding issue.