Tessa: You don't remember me?
Dean: Honestly, if I had a nickel for every time I heard a girl say that...

Go have your Robin Williams "Oh Captain! my Captain!" moment.

That ghost is dead. I'm gonna to rip its lungs out! Well, you know what I mean.

Dean: All right, everybody stay where you are. You'll be okay.
Jock on Bus: Aren't you the P.E. teacher?
Dean: Not really. I'm like 21 Jump Street. The bus driver sells pot. Yeah.

So what's our cover? FBI, Homeland Security, Swedish exchange students?

Sam: Wow, it's like a magic museum.
Dean: You must be in heaven.

Dean: What a douchebag.
Sam: That's Jeb Dexter.
Dean: I don't even want to know how you know that.
Sam: He's famous, kind of.
Dean: For what, douchebaggery?

Dean: I can't believe people actually fall for that crap.
Sam: It's not all crap.
Dean: What part of that was not a steaming pile of B.S.?

Danny: You hunt ghosts?
Dean: That's right.
Danny: Like Scooby-Doo?
Dean: Better.

Dean: Dog: it's what's for dinner.

What kind of ghost messes with a man's wheels?!?

Sam: It's probably a dumbwaiter. All these old houses had them.
Dean: Know-it-all.
Sam: What?
Dean: What?
Sam: You said...
Dean: What?
Sam: Never mind.

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean