Alex: Come on. (takes out her hair piece, and some hair comes with it. Izzie touches and pulls more out) Hey, hey, it's okay. It's just hair, you don't need it.
Izzie: It's just gonna keep falling out.
Alex: We'll shave it off. I bet you'd look good bald anyway. Ok? (Izzie starts crying) Hey, stop. You're beautiful. (Alex kisses her)

IZZIE: "You're tall."
DENNY: "I know."

Izzie: And I know you care about me too and it's not too late for us.
Alex: Get outta my room.
Izzie: Admit it. I know you care about me too I know you do. I care about you. I care about you. I care about you. I care about you. I care about you! I- [they kiss]

Meredith: You're laughing?
Alex: She's laughing.
Izzie: [laughing] George is dead! He's dead! They're about to put him in the ground and the priest is doing classic rock lyrics! And that girl, that redhead, is crying harder than his mother and she never even met him!
Cristina: You are far more twisted than I ever realized.

GEORGE: "You don’t know. Maybe I’ve been sleeping around. Maybe I got ladies."
IZZIE: [smirks]
GEORGE: "Shut up! What am I gonna do?"
IZZIE: "It’s no biggie. A couple doses of penicillin will knock it right out."

Cristina: You will marry... general surgery. Or, you know, okay, perhaps neuro. But you, you are nowhere near hardcore enough to commit to cardio.
Izzie: So you are telling me to... stop flirting with your husband. Haha, I get it. That’s cute. But if you’re going to ask me a favor... insulting my personal life is probably not a great tactic.
Cristina: No, no, wait, I am not talking about your sex life. I could not care less about your sex life. It’s a skydiver. Izzie. A skydiver.
Izzie: Oh yeah, sounds real cool. Enjoy.

"Eating is a sport?"

IZZIE: "So the beer’s coming at 7:00 and some of the floor nurses are bringing wine."
CRISTINA: "You invited nurses? Ugh."
GEORGE: "Did you clear this with Meredith?"
IZZIE: "A few more people isn’t going to make a difference. Okay? A party’s a party."
CRISTINA: "The bigger the party the less time for bad sex with the hockey player."
IZZIE: "Would you stop saying that."
CRISTINA: "Okay."

MARK: "Thought you might be fun to look at while I worked."
IZZIE: "Will you be working on the nerve graft and the skin reconstruction?"
MARK: "Yes, and I think I'll handle them a whole lot better with a little caffeine in my system. Get me a blueberry scone and a bone-dry cappuccino, and a lil' something for yourself."
IZZIE: "There's a cafeteria on the second floor and a coffee cart in the lobby."
MARK: "Fiesty."

Cristina: What are we looking at?
Izzie: Meredith put her Mom in a baggie and brought her to work.
Meredith: I had to get her out of my closet, she was haunting me.
Alex: Now she’s haunting us all.

Alex: You stole my surgery!
Izzie: Using me as a doormat is one thing. Screwing with my career is another! I have been wiping your snot and covering your ass for weeks now. And all you've done is abuse me. And for a little while you get to do that because you're heartbroken and pathetic, and I'm a good friend. But it ends now. Get your own surgery and wipe your own snot.

Izzie: They tried number 9? Who does 9?
Sadie: Well personally I'm a fan of 5, 7, 8, pretty much 12 through 20.
Meredith (laughs): I would try 15.
Izzie: Don't. Don't try 15. I would try 16. Yeah. I've never done that before.
Alex: You'd try 16?
Izzie: Uh huh. I would. I totally would. (Izzie and Alex look at each other then quickly leave the table)
Lexie: Um, don't do 16 too fast. It can hurt badly ... I heard.

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey