PRESTON: "What do you want?"
CRISTINA: "What..."
PRESTON: "What do you want? You don't want to go out to dinner. You don't want to meet me in the on call room, and you sure as hell don't want to talk to me. I could pretend that I know, but hey, I don't even have your home phone number. So what do you want!?"

PRESTON: "You forged my signature?"
MEREDITH: "That’s really bad, right?"
PRESTON: "Yeah, that’s really bad." [pauses] The next time you decide to forge my signature, let me know. Save me a trip."
MEREDITH: "That’s it? You're not gonna yell and say 'Dammit, Grey' and then storm off?"
PRESTON: "I will if you want me to."
MEREDITH: "That's okay."

CRISTINA: "I am wearing the dress. I'm ready. And, and maybe I didn't want to before. But I want to now. I really think I want this."
PRESTON: "I really wish you didn’t think. I wish that you knew."

CRISTINA: "What’s up with your hair?"
PRESTON: "Leave the man alone. He’s got issues. If he wants to cut his hair to get over his issues, that’s his business. That's his thing."
GEORGE: "It's my thing!"

PRESTON: "You were gone when I woke up."
CRISTINA: "I had to go do a thing."
PRESTON: "A thing."
CRISTINA: "Yeah. A thing."
PRESTON: "You didn’t leave a note."
CRISTINA: "Sorry."
PRESTON: [sighs] "We go to sleep, I think everything's fine. We wake up, and you're just a little bit crazy."
CRISTINA: "I had a thing!"

PRESTON: "What the... what the hell is this? Does anybody know what this is?"
MEREDITH: "Oh my God."
PRESTON: [holds body part] "What is it, Grey?"
MEREDITH: "She bit it off-"
PRESTON: "What is it? Spit it out, Grey."
MEREDITH: "That's his.. penis."

PRESTON: "Dr. Stevens! You coming or going?"
IZZIE: [pauses] "I'm not sure. You?"
PRESTON: "I'm not sure either."

MIRANDA: "These are your letters of support for my free clinic. Sign them."
PRESTON: "Why do you want this clinic so badly?"
DEREK: "You're a surgeon."
MIRANDA: "Because I need something more. I know you all have your messy love lives and your secrets and your silliness, but I want more. I need something to hold on to. I need a reason to believe that medicine can do more than stitch you up and send you away. I need to believe that medicine can not only save lives, but change lives! I need... I need... to believe in something the way I used to believe in you all. Sign the papers! Sign the papers."

ADDISON: "I gotta tell you. This group of interns..."
PRESTON: "Emotional."
ADDISON: "Headstrong."
PRESTON: "Hot-headed, stubborn. They think they know everything. You can only give them so much rope before they hang themselves with it. They lose all rationality, they won't listen to reason."
ADDISON: "Jeez, Preston. Don't hold back."

PRESTON: "The Chief is working on her."
DEREK: "He threw me out."
PRESTON: "What do you need?"
DEREK: "I need you to go in there."

PRESTON: "Why are you in this line?"
CRISTINA: "It’s the syphilis line."
PRESTON: "You don’t need to be in this line."
CRISTINA: "I don’t?"
PRESTON: "There’s no one else. That surprises you?"
CRISTINA: "Nothing surprises me."
PRESTON: "Do I need to be in this line?"
CRISTINA: "No."
PRESTON: "Okay then."
CRISTINA: "Okay."

PRESTON: "Dr. Shepherd."
DEREK: "Dr. Burke. Hey. We’ve known each other for a while."
PRESTON: "Yes."
DEREK: "We’ve done several successful surgeries together."
PRESTON: "Yes."
DEREK: "Your girlfriend is my ex-girlfriend's best friend."
PRESTON: "Yes."
DEREK: "So, why don’t we call each other by our first names?"
PRESTON: “I don’t think so."
[Later]
ADDISON: "Hey, Preston."
PRESTON: "Good to see you, Addison!"
DEREK: "She gets to call you by your first name and I don't?"
PRESTON: "I like her."
DEREK: "You don't like me?"
PRESTON: "No."

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey