You don't know me. You never did, and you never will.

Sam: Becky, does he know where it is?
Becky: In a castle on a hill made of forty-two dogs.
Dean: Forty-two dogs?
Sam: Are you sure you got that right.
Becky: It doesn't make sense, but that's what he said. I memorized every word... for you.
Sam: Umm... Becky, can you... quit touching me?
Becky: No.

Sam: I brought this on.
Bobby: You're damn right you didn't listen. You were reckless and selfish and arrogant.
Sam: I'm sorry.
Bobby: Oh, yeah? You're sorry you started Armageddon? This kind of thing don't get forgiven, boy. If, by some miracle we pull this off... I want you to lose my number.

Dean: You're gonna go out there again?
Sam: Well, crap doesn't hit the fan with coffee breaks.

Sam: Thank you. Really. Thank you. I won't let you down.
Dean: Oh, I know it. I mean, you are the second-best hunter on the planet

Dean: Dude, he's short.
Sam: Hey, Gandhi was a great man.
Dean: For a Smurf.

Dean: Let me get this straight. Your, uh, ultimate hero was not only a short man in diapers, but he was a fruitarian.
Sam: That's not the point.
Dean: That is good. Even for you, that is good

Dean: Not a word.
Sam: Dude, you just got whaled on by Paris Hilton.

Sam: Dude, what the hell?
Dean: I had a hunch I went with it.
Sam: You risked my ass on a hunch?
Dean: You're fine. Besides now we know who's turning this town into Willy Wonka's worst nightmare.

Dean: Yeah, everything Jesse believes comes true. He thinks the Tooth Fairy looks like Belushi, uh, joy buzzers really shock people, boom that's what happens.
Sam: Yeah, but convince him that joy buzzers don't actually work and they go from killer machines back into crap toys.
Dean: Probably doesn't even know he's doing it. How is he doing it?

Sam: Oh, d-dude... that's not what I think it is, is it?
Dean: I got bored. That nurse was hot.
Sam: You know you can go blind from that, too.

Sam: It's probably a dumbwaiter. All these old houses had them.
Dean: Know-it-all.
Sam: What?
Dean: What?
Sam: You said...
Dean: What?
Sam: Never mind.

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean