"When Derek broke up with you, nobody told you were better off without him. It's not supportive, it's condescending. I was there for you, and the one time I need you? Just go away, Meredith."


DEREK: "The first person I killed? I was a second-year resident. James Hanson. Go home, Dr. Karev. There's nothing you can do for him now."
ALEX: [pauses] "No one should die alone."

[to Alex] "Look, you screwed up. Mr. Martin's fried. He wakes up, you fried his brain. He dies, you killed him. Deal with it."


IZZIE: "I'm telling you, Meredith was all over him."
CRISTINA: "Seriously, she was all over him? What, like mounting him, with all the babies watching? Seriously?"
IZZIE: "Well, she would have if I hadn't interrupted."
GEORGE: "She was talking to him."
IZZIE: "You don't talk to bastards who cheat on their girlfriends, George. That's the rule."
GEORGE: "You weren't officially his girlfriend."
IZZIE: "That's not the point."
GEORGE: "It is kind of the point. You don't see me getting all emotional over people I'm not dating."
IZZIE: "Really. You wanna go there?!"
GEORGE: [pauses] "No."
IZZIE: "I'm having a moment here. Don't mess with me!"
CRISTINA: "You're not going to have a nervous breakdown and kill yourself, are you?"
IZZIE: "No."
CRISTINA: "So, there's no chance you'll kill us?"
IZZIE: [storms off]
GEORGE: [tries to hide smile] "Okay, that was wrong on so many levels."
CRISTINA: "But it was good though?"
GEORGE: [laughs] "Yeah, it was."
CRISTINA: [laughs]

"You're not here to make friends, Addison. You're here to make better surgeons. Being a teacher can be a lonely business."


OLIVIA: "He dumped me for a girl he knows he can't have. Listen to me George. You, Meredith Grey? Never going to happen."
GEORGE: "Why, why, why would you even... why? Meredith?"
OLIVIA: [storms out]
GEORGE: [to patient] "She gave me syphilis."

[to George, Olivia] "You know what time it is? Time for you two kids to kiss and make up, that's what time it is!"


CONSTANCE: "He said he would leave me if I didn't help him. Things got out of control. He was gonna leave me. He was all I had."
CRISTINA: "Clearly being alone has its benefits."

"One day? Four razor blades and that's all you can give me? Come on, sugarplum, I thought we were having fun."


IZZIE: "You tell me to cut my losses, that I'm better off without him, and as soon as I turn my back..."
MEREDITH: "C'mon! Alex and I are kind of friends."
IZZIE: "Since when? When did you and Alex become friends?"
MEREDITH: "Don't you think you're overreacting? It's not like I'm going to sleep with him."
IZZIE: "Why not, you've slept with everyone else."

GEORGE: "Why Alex? And why again?"
OLIVIA: "People get lonely, George."

[to himself] "Of course. Crazy nature man! Wants to take a leech home as a pet."


Grey's Anatomy Season 2 Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

ADDISON: "There is a land called Passive Agressiva, and I am their queen."
DEREK: [smiles] "That's all I'm saying... except when you're shrieking about trout."