Dean: You know I hate shots.
Sam: I hate demons.

Which one of us is really the monster?

Dean

Oh you were a demon, I didn't realize that.

Sam

Dean: I never said thank you. So...
Sam: You don't ever have to say that, not to me.

You've been kicked, bit, scratched, stabbed, possessed, killed. And you sprain your friggin elbow?

Dean

Yeah, well this fleabag looks like she ain't done chowing down on Sons of Anarchy just yet.

Dean

Maybe I'm not ready to hunt. But I am just trying to do the right thing, man. 'Cause I am so sick and tired of doing the wrong one.

Dean

Not bad.

Chuck

Dean: They're rehearsing the BM scene.
Sam: The bowel movement scene?

There's robots. And tentacles. And space. I can't even.

Calliope

There's nothing in there that remotely suggests there isn't a case. Boom.

Dean

You can't spell subtext without s-e-x.

Marie

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean