What’s up, doc?

Dean

Let me guess, Rog. You were framed?

Sam

Dean: Killer clown? Are you serious?
Sam: No, I'm kidding, because clowns are really funny to me.

Sully: If I show you all we can see, you can’t tell a soul.
Dean: Yeah because chicks dig the whole imaginary friend thing.

I'm a Winchester. I hunt monsters.

Sam

Sam, you saved the world.

Sully

Sam: His blood is glittery?
Sully: Even when he’s dead, Sparkle can’t stop shining.

Get the hell out of hell.

Crowley

Snapping necks and cashing checks, it's what i do.

Lucifer

Dean: Where's Sam?
Crowley: Don't worry about Sam.
Dean: Oh I'm sorry, have you met me?

I'm ready to die. And I'm ready to watch people I love die. But I'm not ready to be your bitch.

Sam

Dean: Your hand is still on my knee.
Mildred: I could move it up.

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean