Dean: Hey. We need to talk.
Lucifer: Dean, even for you, this is a whole new mountain of stupid.

In between jobs, Sam and Dean would sometimes get a day - sometimes a week, if they were lucky. They'd pass the time lining their pockets. Sam used to insist on honest work, but now he hustles pool, like his brother. They could go anywhere and do anything. They drove a thousand miles for an Ozzy show. Two days for a Jayhawks game. And when it was clear, they'd park her in the middle of nowhere, sit on the hood, and watch the stars... for hours... without saying a word. It never occurred to them that, sure, maybe they never really had a roof and four walls but they were never, in fact, homeless.

Chuck

Castiel: It's starting.
Dean: Yeah, you think, genius?
Castiel: You don't have to be mean.
Dean: So, what do we do now?
Castiel: I suggest we imbibe copious quantities of alcohol... just wait for the inevitable blast wave.
Dean: Yes, well, thank you, Blutarsky.

Lucifer: Sorry if it's a bit chilly. Most people think I burn hot. It's actually quite the opposite.
Dean: Well, I'll alert the media.

The Impala, of course, has all the things other cars have... and a few things they don't. But none of that stuff's important. This is the stuff that's important. The Army man that Sam crammed in the ashtray--it's still stuck there. The Legos that Dean shoved into the vents. to this day, heat comes on, and you can hear 'em rattle. These are the things that make the car theirs. Really theirs. Even when Dean rebuilt it from the ground up, he made sure all these little things stayed. 'Cause it's the blemishes that made her beautiful.

Chuck

Sam: Take care of these guys, okay?
Castiel: That's not possible.
Sam: Then humor me.
Castiel: Oh. i was supposed to lie. (chuckles) Uh... sure. They'll be fine, I...
Sam: Just - just stop... talking.

So this is Dr. Evil's lair, huh?

Dean

Dean: Well, I got to ask. How old are you?
Death: As old as God. Maybe older. Neither of us can remember anymore. Life, death, chicken, egg. Regardless - at the end, I'll reap him, too.
Dean: God? You'll reap God?
Death: Oh, yes. God will die, too, Dean.

Dean: So please tell us you have actual good news.
Bobby: Chicago's about to be wiped off the map. storm of the millennium. Sets off a daisy chain of natural disasters. Three million people are gonna die.
Dean: Huh.
Castiel: I don't understand your definition of good news.

Disease gets a bad rap, don't you think? For being filthy. Chaotic. Uh, but really, t-that just describes people who get sick. Disease itself... very... pure. Single-minded. Bacterium have one purpose--divide and conquer. That's why, in the end... it always wins. So, you've got to wonder why God pours all of his love into something so messy... and weak. It's ridiculous. All I can do is show him he's wrong, one epidemic at a time.

Pestilence

That's the beauty about improv, Sammy. You never know what's gonna come out of your mouth.

Dean

Castiel: You said "no" to Michael. I owe you an apology.
Dean: Cass. I-It's okay.
Castiel: You are not the burnt and broken shell of a man that I believed you to be.
Dean: Thank you. I appreciate that.
Castiel: You're welcome.

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean