Sam: His blood is glittery?
Sully: Even when he’s dead, Sparkle can’t stop shining.

Sully: If I show you all we can see, you can’t tell a soul.
Dean: Yeah because chicks dig the whole imaginary friend thing.

What’s up, doc?

Dean

Let me guess, Rog. You were framed?

Sam

Dean: Killer clown? Are you serious?
Sam: No, I'm kidding, because clowns are really funny to me.

What he did? Creation? That took work. That took sacrifice. In order to create the world, God had to give up the only thing he had ever known. He had to betray and sacrifice his only kin, The Darkness, his sister.

Metatron

Do you have any idea how much stuff I had to steal, then pawn, to pay for that?

Metatron

Fatherhood changes a man.

Crowley

I gotta get out of this doily coffin.

Dean

Dean: Bottled toilet water? Why do you keep spraying it?
Sam: I wanted to see if the squeezy thing worked.

Sam: Maybe We're dealing with a serial killer?
Dean: You'd love that wouldn't you.

Dean, people valet park all the time. Come on, live a little.

Sam

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean