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Dr. Maddox (Courteney Cox) comes in as a replacement for Dr. Kelso. Meanwhile, J.D. struggles to manage the new interns and Carla puts Elliot's ego in check.
J.D. attempts to void talking to Kim about her pregnancy; Dr. Cox deals with anger issues.
J.D. and Kim's romance escalates, but Elliot, who recently became friends with Kim, won't give them time alone. Dr. Cox and Jordan celebrate Jack becoming potty trained.
J.D. falls for Dr. Kim (Elizabeth Banks) after she removes her wedding ring and instantly appears; Elliot considers breaking up with Keith when he refuses to stand up for himself.
After five years of working at Sacred Heart, J.D. gets the funny feeling the same events keep occurring. Meanwhile, Cox returns to work but loses his self-confidence.
Feeling guilty over the death of three patients, Dr. Cox comes to work drunk and is forced on a league of absence. The whole staff except J.D. takes rotations visiting Cox.
After repeatedly running into and blowing off an annoying patient, Jill (Nicole Sullivan), J.D. feels guilty when she commits suicide via a drug overdose and he never saw the signs coming.
In an episode narrated by the Janitor, J.D. tries to make a video postcard for his mother, but gets locked in the water tower by the Janitor while the Janitor bonds with a quadriplegic patient.
J.D. finds himself lying to protect his visiting brother Dan's feelings; Carla and Turk can't decides on a baby name; Cox is forced to work with Ted.
Carla is forced to do Kelso's normal job of rejecting people's requests; J.D.'s patient who gets a liver transplant recovers while his brother who donated gets worse.