Dr. Girlfriend, now known as Dr. Mrs. The Monarch since her marriage to the Monarch, is the better half of Dr. Venture's arch nemesis, The Monarch, on The Venture Bros.
Dr. Girlfriend is a former super-villain, who wasonce known as Queen Etherea, and now serves as the voice of reason as she stands by The Monarch's side. She has an unusually deep voice which often strikes rumors of her being a transexual, but it has been implied that her voice is due to cigarettes. We'd still look for scars.