Lisa Marie Simpson, voiced by Yeardley Smith, is Homer and Marge's oldest duaghter and the middle child on The Simpsons.  Lisa is very intelligent, plays the saxophone, is a vegetarian, Buddhist, and definitely a bit of a young political activist.  She's basically the complete opposite of her brother, Bart.

Lisa Simpson Quotes

Lisa's Brain: Poor predictable Bart. Always takes 'rock'.
Bart's Brain: Good ol' 'rock'. Nuthin' beats that!
Bart: Rock!
Lisa: Paper.
Bart: D'oh!

Lisa: Dad, I think he's an ivory dealer! His boots are ivory, his hat is ivory, and I'm pretty sure that check is ivory.
Homer: Lisa, a guy who's got lots of ivory is less likely to hurt Stampy than a guy whose ivory supplies are low.

The Simpsons Quotes

Homer: (Wearing glasses) The sum of the square roots of any two sides of an isosceles triangle is equal to the square root of the remaining side!
Man: (From inside a bathroom stall.) That's a right triangle, you idiot!
Homer: D'oh!

(Bart shows the whole classroom the tape for his project called, "How Kittens Are Born: The Ugly Truth")
Bart: and here comes Snowball II. This is the one we kept.
All: EWW!!
Bart: We were gonna keep the gray one, but the mother ate her.
All: EWWWWW!!
Martin: Mrs. Krabappel, he's traumatizing the children!
Mrs. Krabappel: As usual, I agree with you, Martin. Bart, shut that off and take your seat immediately!
Bart: Oh, look! This is really cool. When I hit reverse, I can make 'em go back in.
(The whole classroom screams)