Dean and Sam
Jensen Ackles stars as Dean, and Jared Padalecki as Sam, on Supernatural. These two anchor the series.

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Supernatural Quotes

You're wrong. I am utterly indifferent to sexual orientation. On the other hand, I cannot abide hypocrites like you, Reverend. Tell your flock where your genitals have been before you speak for me.

Castiel

I'll interrogate the cat.

Castiel