Tom Cavanagh returns to Scrubs as he reprises the role of J.D.'s brother, Dan Dorian. He blames Cox for turning J.D. cynical.

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Scrubs
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Scrubs Season 3 Episode 5: "My Brother, Where Art Thou?"
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Scrubs Season 3 Episode 5 Quotes

Dan: Hey, listen, Dr. Cox: No offense, I'm a big fan of the tough-guy act, but let me tell you what I really think. I think you love the fact that these kids idolize you. Johnny does! Johnny was always the one in the family we knew was going someplace - sweet kid, smart kid. Becoming a doctor, this is all he ever wanted; and yet, somehow, you've found a way to beat that out of him, haven't you? Turned him into some cynical guy who seems to despise what he does. Dr. Cox, Johnny's never gonna look up to me. Ever. But he hangs on your every word. So, I'm askin' - I'm telling you - take that responsibility seriously; stop being such a hard-ass, otherwise you're gonna have to answer to me.
J.D.'s Narration: Love can give you strength you never knew you had.
Dan: It was good seeing you, Dr. Cox.
Dr. Cox: Good to see you, Dan. All the best.

Dr. Cox: Well, Mr. Pickles, welcome back.
J.D.: Here we go with this guy again.
Dr. Cox: Yep. Still, it sure is nice to be doing something you love. I wouldn't trade it. How 'bout you?
J.D.: No...
Dr. Cox: Don't forget that.
Mr. Bober: Pickles.
Dr. Cox: Damn right, sir. Damn right.