It's a personal and existential crisis for Jack as he marks his 50th birthday. Oh, and an entertaining crisis, as well.
Liz Lemon in "Apollo, Apollo" from the third season of 30 Rock. Tina Fey is just the best.

30 Rock Season 3 Episode 16 Quotes

Frank: My god, He's mortal!
Lutz: What just happened!?

Former sexual partner, I'm sorry my disease made you a victim of my sexual charisma. I'm sorry I ruined you for other men.