It's a personal and existential crisis for Jack as he marks his 50th birthday. Oh, and an entertaining crisis, as well.
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Liz Lemon in "Apollo, Apollo" from the third season of 30 Rock. Tina Fey is just the best.
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30 Rock Season 3 Episode 16 Quotes

Frank: My god, He's mortal!
Lutz: What just happened!?

Former sexual partner, I'm sorry my disease made you a victim of my sexual charisma. I'm sorry I ruined you for other men.

Dennis