Quagmire, Peter and Joe are determined to help Quagmire's sister on the episode "Screams of Silence: The Story of Brenda Q."
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Family Guy Season 10 Episode 3 Quotes

Lois:Oh my god, not that guy. Isn't he the one that beats her?
Peter: Yea, but she's gotten a LOT better.

Joe: Oh my god, he must have hung himself during auto-erotic asphyxiation!
Peter: While watching clown porn!