A photo from the episode "A Change is Gonna Come."
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You knew we weren't going to pass that one up. Izzie does some research in order to save the life of a deer friend. Boy, this is just too easy.
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Miranda Bailey is in charge, even if her title doesn't say she's Chief Resident. Alex Karev knows it too.
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Meredith Grey has interns of her own now... one of whom is a very familiar face. There's another one who's her sister, who is under Cristina. The world of troubles continues!
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Unfortunately, for him, Alex Karev that is, Callie Torres is calling the shots. You would never have guessed it but he finds himself missing Dr. Bailey.
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Alex and Callie talk to their patient, unaware that he is about to eat everything in sight. But what are you gonna do.
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There's a new gang at Seattle Grace now. How will the young surgeons we've come to know and love react to this new crew?
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At least Izzie Stevens is trying to convey that message. She is having a tough time on this day at Seattle Grace, however.
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Izzie restrains a young visitor to the hospital. She's having quite the hectic day at the office.
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Eh, that couple nickname just doesn't work. Neither does the chemistry between these characters. Right, fans?
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What does the future hold for Meredith Grey and Derek Shepherd? Hopefully, only love. But we know it's never easy.
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Lexie Grey. Meredith Grey. Face-off. What will transpire as the two sisters must work together at Seattle Grace?
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Grey's Anatomy Season 4 Episode 1 Quotes

I tell you that I love you, and not one word? For 17 days? Where have you been?

Izzie

[narrating] In the practice of medicine, change is inevitable. New surgical techniques are created, procedures are updated, levels of expertise increase. Innovation is everything, nothing remains the same for long. We either adapt to change, or ... we get left behind.

Meredith