House has reason for concern in this photo. Cuddy's mother is very sick on the episode "Family Practice."
Cuddy's mother is the patient on this episode of House. Things get very intense as a result.

House Season 7 Episode 11 Quotes

Arlene [to Cuddy]: If you're going to dress like an Italian hooker, at least let it be this year's Italian hooker.
Julia: She's not telling us we look fat. That's a major breakthrough.
Arlene: If you didn't want to be insulted, you wouldn't have invited me.

Arlene: You think I'm a hypochondriac?
House: Well, let me answer this way: maybe you're imagining that I think you're a hypochondriac.