Homer and Flanders make great partners in crime.
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Jon Hamm lends his voice to The Simpsons for that show's 12/12/10 episode. He portrays a FBI agent who clashes with Homer.
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Martha Stewart appears as herself on the 12/5/10 episode of The Simpsons. This is a shot of the homemaker in that familiar role.
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Danica Patrick and Rachel Weisz lend their voices to characters in the upcoming Simpsons episode, "How Munched is That Birdie in the Window."
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Lisa stands up for Mr. Burns on the upcoming Simpsons episode, "The Fool Monty."
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Marge makes a big sacrifice for her daughter in the upcoming Simpsons episode, Lisa Simpson, This Isn't Your Life."
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Daniel Radcliffe lent his voice to Edmund during a Twilight parody for The Simpsons' "Treehouse of Horror XXI."
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This is the animated version of Hugh Laurie, courtesy of his 11/7/10 guest-starring gig on The Simpsons. Not much of a resemblance is there?
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The Simpsons Quotes

Homer: (Wearing glasses) The sum of the square roots of any two sides of an isosceles triangle is equal to the square root of the remaining side!
Man: (From inside a bathroom stall.) That's a right triangle, you idiot!
Homer: D'oh!

Wow, now I see why they call you Miss Hoover. You must have been vacuuming for an hour.

Bart