Chuck: What are YOU doing HERE?!
Blair: He's just upset, and loaded-
Chuck: What are YOU doing at my father's funeral? You think I WANT you here?
Dan: Chuck, if this is about the article, you know I didn't write it.
Chuck: You think I CARE about your failed attempt at investigative journalism?! My father's DEAD because of your father.

(Bree has stopped Danielle's party because a candle has run out)
Julie: Is she serious?
Danielle: Welcome to my own private hell.

Jordan: Oh, yeah, Ted, I moved the file cabinet. I'm gonna miss this office.
Dr. Cox: Why? It smells like that odd combo of flopsweat, hopelessness, and feet.

Jess, if she dies, I am, I, yeah, I just, please. Please.

Murphy

Kelly: I've missed you so much.
Zack: I missed you too.
Kelly: Please honey let me in. There is so much I have to tell you.
Zack: But I can't, you're...
Kelly: Look at me, you can see that that's not true. I was sick, very sick, but I'm getting better. Just let me in and I'll explain everything.

We are living in a dark, dark age and you are part of the problem.

Janey-E Jones

Kevin: Jackie? Thank you.
Jackie: For what?
Kevin: For putting up with me.

By the power vested in me, I pronounce you husband and wife. [beat] You should smooch.

Jimmy

Turk: I'd watch a show with the Fonzi and a gremlin.
J.D.: Fonzi couldn't take care of a gremlin, he's too busy being cool.

Okay, she did not have to tell me that.

Pete

Meg: (after Joe and the cops take her away) Aaaaah! Dad! Help me!
Peter: Have fun at the dance, Meg! I hope she does. That kid really deserves it.

Hardison: [doing little dance] Get it, get it, get it.
Nate: Is that really necessary?
Hardison: The man put me in a coffin, Nate, a damn coffin
Nate: That's true.