Sheldon: This is now the only lab with glassware washed by a man with two doctorates and a restraining order signed by Carl Sagan.
Amy: Soap spots. Wash them again.

Sheldon: I've seen things. Lady things.
Amy: Listen to me. That is not the way they usually look.
Sheldon: It doesn't matter. This is no way to make new humans. People coming out of people. Some kind of dirty magic show.

Penny: Please come home and let me cut your hair.
Sheldon: Amy what do you think?
Amy: There's not a hair on this body I wouldn't let this woman trim.

The world of science needs more women, but from an young age we girls are encouraged to care more about the way we look than the power of our minds.

If you'd let me pierce your brain with a hot needle in the right place you'd be happy all the time.

Amy: Oh my.
Sheldon: Excuse me, you aren't supposed to be enjoying this.
Amy: Then maybe you should spank me harder.
Sheldon: Maybe I will.

Amy: I feel like I'm in high school again.
Bernadette: Yeah, doing the prom queen's homework, so she'll like us.
Amy: I know. It's finally working.

Penny: If Harry Potter's wand can make decisions, why can't Thor's hammer?
Amy: Ok, if you're going to start comparing wands and hammers, I can't even take you seriously.

Amy: All right, well, who's the best superhero?
Stuart: Shh! You can't ask a question like in here. Are you trying to start a rumble?

Amy: All I'm saying is we live in a world where closure isn't always an op...
Sheldon: ...tion. Okay.

Amy: I'm Raggedy Ann and he's Raggedy C-3PO.
Sheldon: It was a compromise. I lost.

Wil Wheaton: You do realize I'm doing this for free, right?
Amy: Yes and so far we're still not getting our money's worth.

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?