Derek: I am calling post-it, Zola, Bailey, the tumors on the wall, ferryboat scrub caps. I thought D.C. was everything. I was wrong. You... you're everything. I love you and I'm not going to stop loving you. I can't live without you. I don't want to live without you, and I'm going to do everything in my power to prove it.
Meredith: I can live without you, but I don't want to. I don't ever want to.

Meredith: It seems like you came home because you thought you were in trouble.
Derek: I came home because we're on trouble. I came home to work on us. I came home.

Meredith: I'm going to miss you.
Derek: This can work. We can make this work. We will.

Derek: My resume will kick your resume's ass. I am better than you.
Amelia: Oh my God, there's no limit to your narcissism.
Derek: I have been playing this game longer than you at a much higher level. That is all there is to it.
Amelia: Bite me.

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You wanna stay here and not come with me? Why not? Seems to be a trend recently.

Meredith: I’m taking my son with me because I don’t want his first word to be hypothalamus.
Derek: There are worst first words.

It was a revolutionary glob of spit.

We know that every connection matters. Every connection is crucial and when one is broken, it usually means that the damage has been done. This system of connection compels us to act, choose and behave... sometimes seemingly against our own will, but it is not random at all. It is the map of who we are. We will work to understand ourselves... solve the puzzle of how all the connections work and how all the pieces fit.

Meredith: You pulled a sleeping baby out of daycare to do your dirty work. You're disgusting!
Derek: He's got his mother's sparkle.

Meredith: An hour and a half at the store to buy milk?
Derek: I think I might have closed my eyes in the store parking lot.

He's hungry. My nipples are of no use to him.

He's perfect. He's just perfect.

Grey's Anatomy Quotes

Just because we can live without something, it doesn't mean we have to.

Meredith

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)