I will be Derek Shepherd, the former neurosurgeon who is now a research librarian.

Meredith, I'm alive. We survived. Zola has us both for parents. That's enough.

Always had to be the first.

Derek to Mark

Cristina: What's the t-shirt for?
Derek: I'm going to scream alot, probably pass out.

Mark can buy it. His dreams have always been my dreams.

How's Julia? You impregnate her yet?

Derek: You are making this decision with Cristina.
Meredith: She's not the only factor.
Derek: You should be making this decision with me, your husband.

Meredith: We're staying.
Derek: We're going.

When did I become the advice columnist?

He's happy with the eyeball doctor. So make sure you want him because you want him and not because he's with someone else.

Derek: Come back to me.
Meredith: What's to miss in Neuro?
Derek: Me.

You are so sexy when you are looking at a teratoma.

Grey's Anatomy Quotes

[narrating] "At some point, you have to make a decision. Boundaries don't keep other people out, they fence you in. Life is messy, that's how we're made. So you can waste your life drawing lines or you can live your life crossing them. But there are some lines that are way too dangerous to cross. Here's what I know. If you're willing to throw caution to the wind and take a chance, the view from the other side... is spectacular."

MEREDITH

Richard: Chin up. Put your shoulders back, walk proud, strut a little. Don't lick your wounds: celebrate them. The scars you bear are the signs of a competitor. You're in a lion fight, Stevens. Just because you didn't win doesn't mean you don't know how to roar.