I will be Derek Shepherd, the former neurosurgeon who is now a research librarian.

Meredith, I'm alive. We survived. Zola has us both for parents. That's enough.

Always had to be the first.

Derek to Mark

Cristina: What's the t-shirt for?
Derek: I'm going to scream alot, probably pass out.

Mark can buy it. His dreams have always been my dreams.

How's Julia? You impregnate her yet?

Derek: You are making this decision with Cristina.
Meredith: She's not the only factor.
Derek: You should be making this decision with me, your husband.

Meredith: We're staying.
Derek: We're going.

When did I become the advice columnist?

He's happy with the eyeball doctor. So make sure you want him because you want him and not because he's with someone else.

Derek: Come back to me.
Meredith: What's to miss in Neuro?
Derek: Me.

You are so sexy when you are looking at a teratoma.

Grey's Anatomy Quotes

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith

You think that true love is the only thing that can crush your heart; that will take your life and light it up or destroy it. Then you become a mother.

Meredith