Owen: That was quite a show this morning.
Derek: I didn't plan it.
Owen: That made it even better. Any regrets?
Derek: No, any regrets to proposing to Cristina?
Owen: None.
Derek: Getting shot turns out to not be the worst thing after all.
Owen: I need a best man. I know I know we're not that close, but I don't know, you being married to the other twisted sister I just thought it makes us brothers or something.
Derek: I'd be honored. It's an honor.
Owen: Thank you.
Derek: You need a bachelor party?
Owen: No.
Derek: Even better.

Callie: Welcome back Doctor Sheppard.
Derek: Thank you Doctor Torres.

The truth is I hate being chief. Chief Webber is our chief.

Derek: I'm not gonna die.
Meredith: Good. Because that would be the worst break-up ever.

[narrating] Yes or no. In or out. Up or down. Live or die. Hero or coward. Fight or give in. I'll say it again to make sure you hear me. The human life is made up of choices. Live or die. That's the important choice. And it's not always in our hands.

[narrating] The human life is made up of choices. Yes or no. In or out. Up or down. And then there are the choices that matter. Love or hate. To be a hero or to be a coward. To fight or to give in. To live. Or die. Live or die. That's the important choice. And it's not always in our hands.

I know your loss. I lost my father when I was a kid. Two guys killed my father for his watch right in front of me. Right in front of me. I didn't become a doctor because I wanted to be god. I became a doctor because I wanted to save lives. Look at me. Please look at me in the eye. I'm a human being. I make mistakes, I'm flawed, we all are. Today I think for you is just a mistake. You want justice you want somebody to pay. You're a good man I can see that in your eyes. Can you see in mine? Can you?

Meredith: At my parties we drink beer and dance on tables.
Derek: Are you insulting my party?
Meredith: It is getting kinda lame out there.
Derek: Duty calls.

Derek: Why did you tell Owen what I told you?
Meredith: I didn't - I told him nothing.
Derek: He came to me and said you knew.
Meredith: No, I told him nothing I just looked at him.
Derek: You looked at him. Meredith, when you are pissed your face says everything your thinking. Now I have a staff that can't trust me.
Meredith: So what am I supposed to do? Control my face?
Derek: Yes, you are control your face.
Meredith: Maybe you shouldn't tell me things that you don't want me to know. Control that.
Derek: Then I cant tell you anything. Then 80% of my day is off limits to my wife and I don't want that.
Meredith: Well, I don't want that either. I'm sorry. But I have to tell Cristina.

I can't staff this office because she is Hunts friend and your flavor of the month.

God bless you.

Derek: If anything should happen to me, I don't want you to just be you.
Meredith: Well we would make pretty babies.
Derek: So you're thinking about it?
Meredith: Oh, I'm thinking about it.

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey