GEORGE: "What am I gonna do about Olivia?"
IZZIE: "Well, for starters, stop sleeping with her. Unless, you want that thing to fall off."
GEORGE: "That's twice that you trash talked the girl I could one day potentially lo- well, not love, but like a whole lot."
IZZIE: "If she gave it to you, you have to tell her."
GEORGE: "Three."
IZZIE: "Fine! She didn’t give it to you. She was a virgin when you met. You still have to tell her so she can get tested."

GEORGE: "You don’t know. Maybe I’ve been sleeping around. Maybe I got ladies."
IZZIE: [smirks]
GEORGE: "Shut up! What am I gonna do?"
IZZIE: "It’s no biggie. A couple doses of penicillin will knock it right out."

IZZIE: "You got syphilis?"
GEORGE: "I don’t know how this happened."
IZZIE: "Of course you do. God, Olivia must be really getting around!"
GEORGE: "Olivia, she’s not like that."
IZZIE: "It’s the new millennium, George. The only people who aren’t like that are the Amish... and apparently you."

IZZIE: "You know what? It's no big deal, you don't have to lie. I get it. You have needs."
MEREDITH: "What is going on out here?"
GEORGE: "Nothing." [walks away]
IZZIE: [to Meredith] "He's freaked out because I caught him playing with little Jimmy and the twins."
GEORGE: [Turns around] "I have a girlfriend!"
IZZIE: [laughs] "Okay."
DEREK [walks out of Meredith's room] "It sounds like fun out here."

IZZIE: "There's no reason to be ashamed. It's normal, healthy even."
GEORGE: "I am not ashamed. 'Cause I wasn't doing anything. I don't have to. I have a girlfriend."
IZZIE: "An imaginary girlfriend?"
GEORGE: "An actual girlfriend."

IZZIE: [knocks] "George. You locked the door I need to take a shower."
GEORGE: "Um... uh, I'll be out in a minute."
IZZIE: "What are you doing in there?"
GEORGE: "It's private!"
IZZIE: "Oh! Oh, God, I get it. I'm sorry." [Smirks] "I didn't mean to interrupt."
GEORGE: "No, it's not that."
IZZIE: "It's okay. Take your time!"
GEORGE: "I am not doing what you think I'm doing."
IZZIE: [laughs] "You know what, there really isn't a need to explain. Just... finish."
GEORGE: "No... I'm coming. Coming out!
IZZIE: [laughs]

[to himself] "This is George, George has a hot date."

GEORGE: "How’s a pompous cocky jackass like you always have women all over him?"
ALEX: "Little bluebell pills. Lots of them."
GEORGE: "Oh, c'mon."
ALEX: "Float like a butterfly, sting like a bee. O'Malley, you think too much. Can’t you see it? You gotta dance and jab, dance and jab! Like me. I am the Ali of this place."

GEORGE: "Paging Dr. Karev-ian!" [laughs]
MIRANDA: "What did you just say?"
GEORGE: "Um, it, it's a joke, Kevorkian, Karev-ian... Alex Karev?"
MIRANDA: "I get the joke. I just don't think it's funny. You see this O'Malley? I make one mistake with this scalpel and this man's dead. My husband, he makes mistakes at his job all the time. As far as I know he's never killed anyone but I have. And YOU WILL. Alex did. He made a math mistake and a man died for it. Run that past your accountant. See how he'd feel if every mistake he made, someone ended up dead. You don't have to like Alex, you don't have to care about him, but you damn well have to be on his side."

GEORGE: [about Mer] "She's gonna be late."
IZZIE: "Maybe not."
GEORGE: "We should wait for her."
IZZIE: "Definitely not. I'm not her mother and you are not her boyfriend... [smiles] ... not yet anyways."
GEORGE: "Stop, okay, I told you I'm not interested."
IZZIE: "Life is short. George. Do you really want to die before you ask her out."
GEORGE: "I do not want to ask her out."
IZZIE: "Do you really want to die a liar?"
GEORGE: "I’m not... dying."

GEORGE: [bringing Meredith coffee] "Ahh! Hot!"
IZZIE: "Wouldn't it be easier to just ask her out?"

IZZIE: [picks up coffee cup]
GEORGE: "Do you even know who’s that was?"
IZZIE: "I’m hoping it was yours."
GEORGE: "Nope."

Grey's Anatomy Quotes

[narrating] "At the end of the day, when it comes down to it, all we really want is to be close to somebody. So this thing where we all keep our distance and pretend not to care about each other, it's usually a load of bull. So we pick and choose who we want to remain close to, and once we've chosen those people, we tend to stick close by. No matter how much we hurt them. The people that are still with you at the end of the day, those are the ones worth keeping. And sure, sometimes close can be too close. But sometimes, that invasion of personal space, it can be exactly what you need."

MEREDITH

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)