Alex: You're having the surgery.
Izzie: What?
Alex: Shepherd said this is your last shot.
Izzie: Look I under-
Alex: I am your husband, and I say that you are having the surgery!
Izzie: What happened to "this is your decision."?
Alex: That was when I thought you were gonna make the right one! But, you chose wrong so now you don't get to make this decision on your own, because you married me! It's not just your life at stake anymore! It's my life too. My life with you! So you can tell Swinder whatever you want, but I'm telling Shepherd, and I'm telling you that you're having the surgery!

Alex: What's going on?
Cristina: Oh, we're just going over Izzie's IL2 schedule.
Alex: Oh, for after the surgery?
Izzie: I decided not to have the surgery.
Alex: What?
Swinder: Maybe we should come back. Dr. Yang.
Cristina: Yeah.

Allison: Don't do it. That's my vote. Don't have the surgery. I didn't. I friggin hate surgery.
Izzie: I'm hallucinating Allison. I have really long conversations with dead people, and i see that aren't... Like right now, for example, I'm pretty certain there aren't birds flying over your head, because this is a hospital and that would be weird. But, that's what I'm seeing. I have a brain tumor. Am I really not gonna let them cut it out?
Allison: I didn't let them cut out mine. It's like... ok, one minute I'm this college kid. Rowing crew, and being an idiot, and forgetting to bring my sunscreen, and thinking it doesn't matter. Because, I'm me, and life has turned out pretty good for me. And then the next minute they're cutting into my body every other week. I had 15 surgeries, and then I said... enough. Forget it. I'll rogue through in heaven, or whatever. And then, the IL2 worked. It worked. I come here every 3 weeks, I get my medicine, and I don't have a brain tumor anymore.

Meredith: You couldn't remember anything. You didn't know my name. You didn't know who Derek was. (Mer tears up) You didn't know who Alex was. You couldn't even remember how to speak.
Izzie: How come I don't remember any of this.
Meredith: Because, the tumor is sitting right in the middle of everything that makes you, you. I was standing there talking to you exactly like i am now, only you weren't there. You weren't you. You were gone.
Izzie: So, what do I do?
Meredith: Well, Swinder has a patient. Female, 22 years old, metastatic melanoma.
Izzie: Allison Clarke?
Meredith: After 3 months of the IL2 her mets were gone. All of them. You're not having this surgery.

Swinder: The test impaired your memory to such a degree that I have to strongly recommend that you don't have the surgery.
Derek: Izzie, the test was the worst case scenario. The result has nothing to do with the surgery.
Swinder: We don't know that.
Derek: But what I do know is that not operating is every bit as risky as the surgery itself. If not more. But, it's up to you.
Izzie: What do you think?
Alex: I think he's talking to you, not me.
Derek: I'll leave you two alone to discuss this.
Alex: Ah, I'll come with you. I have a couple of questions.
Izzie: Wait, Alex.
Alex: Think about what you want to do for a second, ok? I'll be right back.
(everyone but Mer leaves the room. Mer closes the door)
Meredith: You are not having the surgery!

Derek: Now we just wait for the brain activity in that area to stop.
Izzie: Dog, plane, house. Dog, plane, hou....
Meredith: (Der nods to Mer) Ok Izz. Can you tell me what you saw?
Izzie: eh...
Derek: (Mer looks at him scared) Show her the cards.
Meredith: What's this? (Izzie looks at the card) Dog. Can you say dog?
Izzie: (Tries to speak) Nnn... ah.. nnnyahhh...
Meredith: Well, what's my name?
Derek: Just stick to the cards Meredith. (Mer looks at Derek getting more scared)
Izzie: Mmm.
Meredith: Meredith. You know my name, you can say my name.
Izzie: Mmm... Mmmme...
Swinder: This is what I was afraid of.
Meredith: Ok, whose Alex? Izz, ok. You don't have to speak. Just, nod your head for me if you know who Alex Karev is. (Mer looks at Der and is starting to tear up. Izzie looks around really scared.)

Meredith: Ok Iz, I am going to show you a series...
Izzie: A series of images that you want me to try to remember once Derek put the right side of my brain to sleep.
Derek: Mhmmm.
Izzie: Hit me. Show me what you got.
Meredith: Ok.
Izzie: Is that a schnauzer or a scotty? How specific do I need to be?
Derek: Dogs fine.
Izzie: It's either a 727 or a 747.
Derek: Plane.
Izzie: Oh, a 2 story victorian mansion.
Derek: We would also accept the word house.
Izzie: Schnauzer, 747, mansion, Schnauzer, 747, mansion...
Derek: Or... dog, plane, house. I'm gonna put the right hemisphere of your brain to sleep now, ok?
Izzie: Dog, plane, house. Dog, plane, house. Dog, plane, house. Dog, plane, house. Dog, plane, house. Dog, plane, house. Dog, plane, house. Dog, plane, house. Dog, plane, house.

Izzie: If Derek cuts the tumor out I could lose my memory, and if he doesn't I can die. I don't know what to do. Alex, tell me what to do.
Alex: Iz, I can't tell you what to do.
Izzie: Of course you can, you're my husband. That's what husbands do, they stomp around telling their wives what to do. It's your job.
Alex: My job is to support whatever you wanna do.
Izzie: I don't know what I wanna do. That's why I'm asking you. Ok, I have an idea. Let's put it to a vote. All in favor of the surgery.
Meredith: No. We're not voting. No ones... no ones voting.
Izzie: Opposed?
Cristina: I'm opposed... to voting.
Izzie: Just decide for me. Please?
Alex: You don't have to know right now. Think about it.
Izzie: I don't have time.

Denny: Nice ring. Alex outdid himself.
Izzie: We're gonna have beautiful kids. Is 4 too many?
Denny: 4 is perfect.
Izzie: Ideally it would be 2 boys, and 2 girls. One of which would definitely be a tom boy. And I was thinking I should have them pretty close together, though that might be stupid.
Denny: Why wait?
Izzie: Exactly. That way if I'm not able to practice medicine anymore...
Denny: You won't want to.
Izzie: You don't think?
Denny: Do you?
Izzie: I'm asking you. Why do you keep agreeing with everything I say?
Denny: Because I am you. I'm your tumor. You're talking to yourself.
Izzie: Right.
Denny: At least until you have surgery. If you have surgery. Are you gonna have surgery?

Swinder: You wanna remove her hippocampus?
Derek: One of them. It's a common procedure for seizure patients
Swinder: Moving her hippocampus could compromise her memory, her speech, she wouldn't be able to practice medicine anymore.
Derek: I have performed this surgery hundreds of times.
Swinder: On cancer patients?
Derek: No. But it's...
Izzie: If you do the surgery I could lose my memory?
Derek: It's unlikely but it's possible.
Izzie: And, if you don't do the surgery...
Swinder: We could shrink the tumor with IL2.
Izzie: If the tumor doesn't kill me first.
Derek: Why take the chance?
Swinder: Have you even done a WADA test to see how her memory would be affected?
Derek: Putting her brain to sleep and asking her to remember a bunch of flash cards is not an accurate assessment of the post surgical outcome.
Swinder: But, it would tell us whether or not she could function afterwards. And, as Dr. Stevens primary physician...
Derek: Fine I'll do it. It's unnecessary but...
Swinder: The surgery is unnecessary.
Derek: The tumor is already symptomatic, she's having hallucinations.

Allison: Can you turn him around so we can see the butt?
Izzie: Yes. Alex?
Alex: Ha, what, are you kidding me?
Izzie: (looks away) Oh! Big trauma just came in! (Alex turns around giving everyone a view of his butt)
Allison: That's quality booty.
Izzie: Right!
Allison: Congratulations Izzie!
Izzie: Thank you.

Alex: Are you sure you're okay to be up and around?
Izzie: Yes. I have good days and bad days. Plus, I don't wanna spend out entire honeymoon in a hospital bed.
Alex: This is not our honeymoon.
Izzie: It totally is. Come on, I want you to meet my friends.
Alex: I know all your friends.
Izzie: You know all my doctor friends. I'm a patient now, you're gonna meet my patient friends, and they're gonna love my new husband.
Alex: Don't make it a big deal.
Izzie: I'm not gonna make it a big deal. (Walks into room) I'M A BRIDE!
(everyone claps)
Alex: Izz, come on. I'm getting her a real one.
Izzie: I love this one. (shows plastic ring) And, that makes it a real one.

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey