Leonard: Put it on the agenda.
Sheldon: You have to make a motion to put it on the agenda.
Leonard: Oh, I'll make a motion, but you're not going to like it

Leonard: Just apologize to him, okay?
Penny: What? I'm not going to apologize to that nut-case.
Leonard: Come on, it's easy. He'll even tell you what to say

Wolowitz: Over the years, we've formulated a number of theories about how he might reproduce. I'm an advocate of mitosis.
Penny: I'm sorry?
Wolowitz: I believe one day Sheldon will eat an enormous amount of Thai food and split into two Sheldons.
Leonard: On the other hand, I think Sheldon might be the larval form of his species and someday he'll spin a cocoon and emerge two months later with moth wings and an exoskeleton

Ramona: You're not going to Halo night
Sheldon: Yes, I am. It's Wednesday. Wednesday's Halo night.
Ramona: Didn't a great man once say, "Science demands nothing less than the fervent and unconditional dedication of our entire lives"?
Sheldon: He did.
Ramona: And who was that great man?
Sheldon: Me. Sorry, Leonard.
Leonard: Seriously? You're not coming?
Sheldon: You heard her. How can I argue with me?

Penny [after witnessing Sheldon and Ramona together]: You probably don't want to go in there.
Leonard: Why? What are they doing?
Penny: The only way I could explain it would be in a therapist's office with dolls

Sheldon: Looking out at your fresh young faces, I remember when I, too, was deciding my academic future as a lowly graduate student. Of course, I was fourteen. And I had already achieved more than most of you could ever hope to, despite my 9:00 bedtime. Now, there may be one or two of you in this room who has what it takes to succeed in theoretical physics, although it's more likely that you'll spend your scientific careers teaching fifth graders how to make papier-mâché volcanoes with baking soda lava.
Leonard: Oh, good God.
Sheldon: In short, anyone who told you that you would someday be able to make some significant contribution to physics, played a cruel trick on you—a cruel trick indeed. Any questions? ... Of course not. I weep for the future of science

Rajesh: Isn't there a University policy against dating graduate students?
Leonard: No. If you can talk to them, you can ask them out.
Rajesh: Damn, there's always a catch

Sheldon: How am I going to get to work?
Leonard: Take the bus.
Sheldon: Oh, I can't take the bus anymore. They don't have seatbelts, and they won't
let you lash yourself to the seat with bungee cords.
Leonard: You tried to lash yourself to the seat with bungee cords?
Sheldon: I didn't try; I succeeded.

Sheldon: Leonard, have you ever wondered why my little toes and lateral incisors are significantly smaller than the average for someone of my size?
Leonard: I wonder a lot of things about you Sheldon, but not that

Raj: Did you see my limo downstairs?
Leonard: Yeah.
Raj: It's bigger than the house my grandfather grew up in.
Leonard: Great.
Raj: It has more food, too

Leonard: It wouldn't kill us to meet new people.
Sheldon: For the record, it could kill us to meet new people

Wolowitz: So you're just going to sit around here and mope while Penny is out with Dr. Apu from the Kwik-E-Mart?
Leonard: It's not a date, and that's racist.
Wolowitz: It can't be racist, he's a beloved character on The Simpsons

TBBT Quotes

Penny: Hey, Sheldon, did you change your Wi-Fi password again?
Sheldon: Yes, it's "Penny, get your own Wi-Fi." No spaces.

Sheldon: Why do you have the Chinese character for "soup" tattooed on your right buttock?
Penny: It's not "soup," it's "courage."
Sheldon: No it isn't. But I suppose it does take courage to demonstrate that kind of commitment to soup.
Penny: How'd you see it? You said you wouldn't look.
Sheldon: Sorry. As I told you, the hero always peeks.