Homer: Marge I believe you're forgetting America's greatest wartime wheelchair-bound leader, Professor X of the X-Men.
Marge: It's not that Professor X wouldn't get up, it's that he couldn't!

Well I guess we've learned that of all the countless planets in the universe, we have evolved into the most inedible species. Like three bean salad at a barbecue, we will remain untouched.

Lisa

Marge: Homer, you have to stop dropping your pants for everyone who claims they're a doctor.
Homer: Fine.

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Lisa: Mom, where's dad?
Marge: I don't know.
Bart: Aw it's Christmas Eve man, we do not want to set a precedent for fat guys being late tonight!

Homer: A-camping we will go
Marge: But where I still don't know
Homer: A place that's filled with sun and sand, a desert steamed from Disneyland, keep expectations low.

You always do the right thing...sort of.

It's like they don't care if you make money, as long as they make money. What kind of corporation does that?

Homie, the fantasy draft just ended. I got you five kickers. It is called football, right?

Homer: Marge, did you replace our regular mirror with a magical mirror from a mystical salesman at a weird store that if we went back to find it it wouldn't be there anymore?
Marge: No
Homer: AAAAHHH!!

Homer: Marge, who would give up eating steak in the matrix to go slurp goo in Zion?
Marge: We don't have that movie here.

Marge:You can live with your no good son.
Bart: Hey, what did I do?
Marge: Nothing for thirty years. You're perfect for each other.

Homer: I am as healthy as a horse.
Marge: Horses only live thirty years.

The Simpsons Quotes

Homer: (Wearing glasses) The sum of the square roots of any two sides of an isosceles triangle is equal to the square root of the remaining side!
Man: (From inside a bathroom stall.) That's a right triangle, you idiot!
Homer: D'oh!

Mayor Quimby: And, uh, may the Force be with you.
Leonard Nimoy: You have no idea who I am, do you?
Mayor Quimby: Sure, I do. You're one of the Little Rascals, right?