Derek: That's my chair.
Mark: I know I like it. Makes me feel powerful.

[lying with Callie and Arizona] This isn't gonna work for me ...

[to Callie] You're MY friend, not hers. Don't you take her side!

[to Lexie] I can't even look at you right now.

Mark: Don't make me choose between you are her.
Lexie: Why? Because you'll choose her?
Mark: Yeah. I'll choose her.
Lexie: I think our relationship just ended.

Because of you, for the first time in my life, I know what the right thing is.

I know I've only been your father for a short time, but I swear, if you say gimp one more time, I'm gonna slap you.

Addison: You told her?
Mark: She's my kid. We were bonding.
Addison: That's now how you bond with children.
Mark: I'm still getting the hang of it.

Addison: Let me say it once: Grandpa... Grandpa, grandpa, grandpa!
Mark: Okay. That was four times. Get it out of your system?

Get me Addison Montgomery!

I'm a surgeon and I'm looking at a time bomb in a uterus. Shut it down now, Addison!

Mark: It's the guilt, you know? It's like every time I look at her... I just... The guilt is like a punch in the gut. Everyday.
Derek: Well, you shouldn't feel guilty, you didn't know.
Mark: I did know. I knew it when her mom got pregnant. She told me. I gave her a couple hundred bucks and I left town and I never saw her again. I figured she got an abortion. Hoped. But I did know.
Derek: Well you're a different guy now. You're not 18 anymore, you've grown up, and you're capable of better.

Grey's Anatomy Quotes

[narrating] "At some point, you have to make a decision. Boundaries don't keep other people out, they fence you in. Life is messy, that's how we're made. So you can waste your life drawing lines or you can live your life crossing them. But there are some lines that are way too dangerous to cross. Here's what I know. If you're willing to throw caution to the wind and take a chance, the view from the other side... is spectacular."

MEREDITH

Richard: Chin up. Put your shoulders back, walk proud, strut a little. Don't lick your wounds: celebrate them. The scars you bear are the signs of a competitor. You're in a lion fight, Stevens. Just because you didn't win doesn't mean you don't know how to roar.