Penny: Yeah, I listen to what you say. You're building a particle detector using superfluid helium.
Leonard: You know, when you talk like that, I want to take you right here on this table.
Penny: And you know from past experience this table cannot support both our weight.

Penny: Sheldon, we are just people. we talk about the same things you guys talk about.
Sheldon: You talk about if werewolves can swim?

I love him, but if he's broken, let's not get a new one.

Sheldon: Nothing more fun than a paradigm shifting evening of science.
Penny: (to Leonard) And you thought it was soaping me up in the shower.

Leonard: Hang on. Why do we have to hate it?
Penny: Three words. Dr. Who Convention.

Penny: Oh, I know. We could go horseback riding.
Amy: Actually I can't. My hips don't open wider than 22 degrees. I rode a very thin pony once. On the first bump I just pssshh, popped right off.

Sheldon: You know, speaking of attorneys,if I ever needed a lawyer,I would not hire She-Hulk.
Penny: You know what? That was almost on topic. I'm gonna say, "Good job, Sheldon."

Bernadette: I mean, maybe I come off a little strong, but that's only because my dad raised me to be tough and not to take
crap from anybody.
Penny: No. That's fine, but there's a difference between being tough and telling your friend her new pants look like a saggy diaper.
Bernadette: I did say that, didn't I?
Penny: Yeah, you did. I felt so self-conscious, I had to return them.
Bernadette: Where? To Babies R Us?

Bernadette: What's his problem?
Penny: Oh. I don't know. Maybe he didn't like the fact that you called his grandson a wuss.
Bernadette: Well, I didn't think you were supposed to say "sissy" anymore.

Dan: Bernadette. Cute, sweet...vicious little Bernadette.
Penny: Come on. She's not that bad.
Dan: Oh, yeah? At the company picnic she yelled at me and my grandson for losing the three-legged race. I mean, he still calls her "that mean kid with the big boobies."

Penny: Okay, the reason he deceived you is you were being
a pain in the ass.
Sheldon: The reason I was being a pain in the B is because I was worried about him, and no one else was.
Penny: Really? You won't even say "A"?
Sheldon: You bet your sweet B I won't.

Sheldon: I assume this medical center's already treated the burns on your bottom from the recent pants fire.
Penny: 'Cause I'm a liar, liar?
Sheldon: That's for the fire marshal to determine.

TBBT Quotes

Penny: Hey, Sheldon, did you change your Wi-Fi password again?
Sheldon: Yes, it's "Penny, get your own Wi-Fi." No spaces.

A neutron walks into a bar and asks, "How much for a drink?" The bartender says, "For you? No charge."