CRISTINA: "What the hell is this?"
PRESTON: "It's a key."
CRISTINA: "Why?"
PRESTON: "Why is it a key? Are we feeling existential this morning?"
CRISTINA: "Well, if the key turns in a lock, and no one asked for the key or even wanted the key, does it make a sound?"

[to Meredith & Cristina] "This is a men's room. Either whip one out, or leave."

[to Cristina] "You do enjoy crossing the line, don't you?"

PRESTON: "I think you should know that Richard promised Chief to both of us... but you already knew that."
DEREK: "Yeah, well, keep your friends close and your enemies closer."
PRESTON: "No. You're not the enemy, you're just the competition."

PRESTON: "Anything you say in the next 30 seconds is free, starting right now."
MIRANDA: "I think you’re cocky. Arrogant. Bossy and pushy. You also have a God complex and don’t think of anybody but your damn self."
PRESTON: "But, I-"
MIRANDA: "Wait. I still have 23 seconds and I’m not done."

PRESTON: "What the... what the hell is this? Does anybody know what this is?"
MEREDITH: "Oh my God."
PRESTON: [holds body part] "What is it, Grey?"
MEREDITH: "She bit it off-"
PRESTON: "What is it? Spit it out, Grey."
MEREDITH: "That's his.. penis."

"The only person that can keep a promise that big is God, and I haven't seen him holding a scalpel lately."

PRESTON: "I guess we never really got our date."
CRISTINA: [smiles] "Are you kidding? That was the best date I've ever been on."

PRESTON: "Dr. Yang, you're handling the saw."
CRISTINA: "You won't let me pick the wine, but this you'll let me do?"

WOMAN IN RESTAURANT: "Oh my God! Is there a doctor here?"
CRISTINA & PRESTON: "Yes!"

PRESTON: "So... it's date night."
CRISTINA: "Yeah, it's a night... with a date."

[the cast, narrating]
MEREDITH: "Human beings need a lot of things to feel alive."
GEORGE: "Family"
CRISTINA: "Love"
IZZIE: "Sex"
DEREK: "But we only need one thing"
RICHARD: "To actually be alive."
CRISTINA: "We need a beating heart."
ADDISON: "When our heart is threatened"
ALEX: "We respond in one of two ways."
GEORGE: "We either run or-"
IZZIE: "We attack."
RICHARD: "There's a scientific term for this."
ALEX: "Fight..."
ADDISON: "...or flight."
MIRANDA: "It's instinct."
MEREDITH: "We can't control it."
IZZIE: "Or can we?"

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Callie: Did anyone ever think you two were a couple?
Meredith: No, because we screw boys like whores on tequila.
Cristina: Then we either try to marry them or drown ourselves.
Callie: Huh.