Leonard: I'm not going to make a fake appointment with a psychiatrist. What would I say is wrong with me?
Koothrappali: Low self esteem.
Howard: Social anxiety.
Sheldon: Sexual insecurity.
Leonard: None of that is true.
Penny: Denial. See sweetie, the list goes on and on.

Raj: You two are as afraid of hurting someone's feelings as I am.
Bernadette: That's not true. We were just laughing right in your face.

Bernadette: I don't when I became the mother to three lazy teenagers, but it stops today. You guys are cleaning the kitchen top to bottom.
Raj: Hey, I don't even live here!
Bernadette: Yes or no, do you have clothes in my laundry right now?

What if he's in prison? What if he's a spy? What if he's in a Beatles cover band? I'm just saying if he's got your nose and haircut, he'd make a killer Ringo.

Nathan Fillion: How about a guy who looks like Nathan Fillion, but a little more annoyed than Nathan Fillion usually is?
Leonard: What do you think?
Raj: Aww. That's good enough for Facebook.

Nathan Fillion: Oh, umm. I think you made a mistake. I'm not an actor.
Raj: Don't say that. You're not Dame Judi Dench but you're pretty great.

Raj: The guy who plays Jon Snow was a jerk and we still watch Game of Thrones.
Leonard: He was a jerk because you rear-ended him.
Raj: I was distracted. It's weird seeing a member of the Night's Watch with kayak strapped to his car.

Leonard: Stephen Hawking liked our paper. Said the premise is intriguing.
Sheldon: Good to see you again, Mr. Stephen-Hawking- Liked-Our-Paper.
Leonard: And you as well, Mr. Our-Premise-Is-Intriguing.
Howard: How do you do, Mr. I'll- Admit-That's-Pretty-Cool?
Raj: Yeah, you keep setting me up for failure.

What kind of scientist are you? everyone knows you've gotta make two out of three!

Raj: No, I'm not okay. I feel like I'm going to jump out of my skin.
Bernadette: I told you not to wax down there.

Leonard: What if... what if this is the thing that would've finally let him open that bottle of champagne?
Raj: Maybe he didn't know what to pair champagne with. Strawberries, caviar, oysters. All good choices. Yeah, that look right there is why people eat before they come to your parties.

Raj: When stuff like this gets me down, you know what I like to do?
Howard: Sing "Hakuna Matata" like an eight-year-old girl?
Raj: Wrong, smarty-pants. It's "Everything Is Awesome" from The Lego Movie.

TBBT Quotes

Penny: What actor holds the record for being named People magazine's Sexiest Man Alive?
Sheldon: William Shatner!
Leonard: I don't think it's Shatner.
Sheldon: Then it's got to be Patrick Stewart

Penny: Here's a question-- as an alien pretending to be human, are you planning to engage in any post-prom mating rituals with Amy?
Sheldon: There are post-prom mating rituals?
Penny: Not always. Unless your date drives a van with an air mattress, then always.
Sheldon: Well, if it's part of the prom experience, then I'm open to it.
Penny: You're kidding.
Sheldon: I may be an alien, but I have urges.If Amy wants to copulate by firing her eggs into space, well, then, I will happily catch them with the reproductive sac on my upper flermin. I'm not the best at reading facial cues, but I can see that you're a little turned on.