[narrating] "Being Chief... is about responsibility. Every single surgical patient in a hospital is your patient. Whether you're the one who cut them open or not. The scalpel stops with you. You need to be able to look at her family. And to tell them your team did everything they could to save someone's life. The husband, the wife. Taking care about the people's families. And responsibility... it makes you... you take care of the people's families. But you sacrifice your own."

MEREDITH: "If you called me here to lecture me..."
RICHARD: "There's a copy of the interns' exam on the table. And a #2 pencil and a bottle of water and a sandwich if you get hungry. I assigned a proctor and I will come back in a few hours to check on you."
MEREDITH: "You're not my father."
RICHARD: [hugs her] "I know that. I know."

IZZIE: "Here she is."
RICHARD: "Thank you Stevens. You can go out."
IZZIE: "I will be waiting right outside."
MEREDITH: "You don't have to."
IZZIE: "Shut up."

RICHARD: "You're not to blame for Susan Grey's death and you know that, and your father knows it too. He's just... well, he's never been the best communicator. And he just lost his wife."
MEREDITH: "Stop acting like my surrogate father."
RICHARD: "Meredith, I'm, um..."
MEREDITH: "Just because you slept with my mother... That does not make you my father!"

MEREDITH: "I was just on my way..."
THATCHER: "No, I came here to tell... You are not invited. I don't want you to come, Meredith."
RICHARD: "But she wants to come..."

PRESTON: "We have been through a lot this year."
DEREK: "And everybody else turned you down. Alright, what do I have to do?"
RICHARD: "Well, traditionally, the best man plans the bachelor party."
DEREK: "Drinks at Joe's after work."
PRESTON: "I knew you were the man for the job."

PRESTON: "Actually, Chief..."
DEREK: "You can't be his best man!"
RICHARD: "Why not?"
DEREK: "It's unethical; it's a conflict of interest. The man wants to be Chief of Surgery."
PRESTON: "Actually, Derek..."
DEREK: "Not that that's why you're asking..."
PRESTON: "I was going to ask you."
DEREK: "Ask me what? [pauses] Oh! Really?"

RICHARD: "Tomorrow's a big day."
PRESTON: "And apart from the fact that Cristina hasn't written her vows, my best man just cancelled, and it's still raining."
DEREK: "He's not ready."
RICHARD: "You're never ready. I certainly wasn't. And then, the minute I saw Adele coming down that aisle... Well. Have you picked your best man?"

RICHARD: "So, how you feeling, Preston? You ready?"
PRESTON: "Well, I'm always ready for surgery."
DEREK: "I think he's talking about the wedding."

MEREDITH: "It looks like a teeny tiny catfish."
RICHARD: "Close. See there? Those are spines. This is a candirú fish."
CRISTINA: "The penis fish? This guy has the penis fish! In his... in his... Wow!"

MARK: "Why? I mean, did she tell you why?"
DEREK: "What did you do to her, Mark?"
RICHARD: "She didn’t give a reason."
MARK: "Did she tell you where she was going?"
RICHARD: "All she said was she needed some time. To be happy and free, if I recall correctly. Excuse me."

MARK: "Has anybody seen Addison?"
RICHARD: "Uh, she’s gone."
MARK: "Gone?"
RICHARD: "She took a leave of absence."

Grey's Anatomy Quotes

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)