Serena: Did you just get a key?
Girl: Yep. And my mom said I'd never get in unless I lost 10 pounds. She's a bitch.

Blair: What about all those rumors about you and Nate?
Serena: Mmm mmm. Not true. They just got people off my back so I could stop being sad, and Nate could go do whatever he wants, so it worked out for both of us.
Blair: You mean you haven't had ANY fun with anyone all summer?
Serena: There's this hot lifeguard that asked me out, but I, you know, I turned him down
Blair: A hot lifeguard is like kleenex! Use once and throw away. You could ask for a better rebound!

"Flighty"? "Irresponsible?" I'm gonna kill him.

Charlie: Dan's standing outside of some restaurant called Veselka. But he's definitely acting weird.
Serena: Veselka. And guilty weird or hungry weird? The man loves his pierogies.

Tripp: Maureen orchestrated a fraud. If you walked out the door this second it wouldn't change a thing. But I hope you won't.
Serena: I have to. You're married and as long as you are, I can't do this.

[to Dan] Okay. I will see you back in the city. Fully clothed. With lots of people around. Okay?

Serena: Sorry if we kept you up last night. We were playing Scrabble.
Ben: She fell asleep to avoid losing.
Dan: Since when do you enjoy Scrabble?

Everything with Gabriel is perfect.

Serena: I noticed the other day that you don't wear a watch. And then it occurred to me it's because you don't have a watch. You're going to need one to be punctual for all the meetings with editors and publishers, now that you're fancy and, apparently, self-important writer... You don't like it. You want the band changed.
Dan: No! I love the band. I love the whole thing. It's the most amazing watch I've ever seen... but I can't accept this.
Serena: What? Yes, you can. Look, it's more of a gift for me because I had so much fun picking it out for you. You have to.
Dan: Serena, I buy a book for my dad every Christmas. I think the most elaborate gift I've ever given has been a pair of rubber boots from L.L. Bean.
Serena: So, then, I overdid it?
Dan: I think even when you're underdoing it, you're overdoing it.

Nate: Tripp? Really? Two months ago you were all over Carter Baizen. Tripp has sacrificed so much to get where he is. We all have. He can't just throw it away on you.
Serena: He's fighting it, and so am I. I can literally feel my heart thump when I see him. I haven't felt this way since I was 13 and saw Jude Law in Alfie.
Nate: Well you're not 13 anymore, Serena.

Serena: When Georgina left town she gave me her laptop and it had a direct link to the Gossip Girl server, passwords, the software, everything.
Blair: S, you had me at Georgina, but I can't believe it. Why didn't you tell me?
Serena: I don't know. I felt like it was something I had to keep secret from everyone. I mean, my best friend even. I know it was wrong and I'm so sorry.
Blair: I mean I could have helped. Sealing fates, forging destinies. Like an imperious Greek goddess. Imposing her will on the guileless masses. But I was wondering why Gossip Girl was being so nice to me lately. And a little off her game. No offense.
Serena: So you're not mad?
Blair: I am furious with you! For not sharing your good fortune and omnipotence. But right now I have to go replace my mother's La Mer before she returns from Paris and discovers I've used it all.

Serena: Don't worry about Dan, I'm sure he'll understand.
Olivia: He hasn't even seen it. I don't know what to do. I have to fix this. In the meantime, I have to keep him away from TV, and the Internet, and strangers with the urge to make fun of him.
Serena: Don't forget about Gossip Girl.

Gossip Girl Quotes

Even Blair Waldorf can not bend DNA to her will.

Dan

Hazel: Do you know what you're doing, Little J?
Jenny: I'm not Little J anymore.