Serena: All I have in my pile are divorce papers, jewelry and artful nudes of my mother in her groupie days.
Chuck: Swap piles?

Serena: And who do we say you are, my son?
Chuck: Is it weird hearing you say that actually turns me on?
Serena: This better be worth the therapy.

Chuck: As I see it, we have two distinct goals. I want to block the sale of Bass Industries, you want to get ol' Ben out of jail. A single strategy may satisfy us both.
Serena: Which is?
Chuck: Blackmail.

Dan: Crazy question, but why isn't Ben just going after Lily himself?
Serena: Because he knows she'll go to the cops and tell them what Juliet did to me.
Dan: Oh, you mean kidnap and drug you?

Dan: I'm sorry. I know you were hoping for some closure.
Serena: Well my mom's deviousness is the gift that keeps on giving, so for now at least the past still lingers.

Serena: So, how was your break? What did you do?
Dan: Why, what'd you hear?

Serena: Just take me away from my problems, please. Tell me, what did you do over the break?
Blair: Why? What did you hear?

Serena: I had to pull an Erin Brockovich and go down to the Litchfield County clerk's office to try to get a copy of the case. And how's this for irony ...
Blair: Court records are public so you wore a push-up bra for no reason?
Serena: The case filed is sealed because it involved a minor.

Ben: Serena? What are you doing here?
Serena: I had to come see you.
Ben: I don't know what to say.
Serena: Neither do I. But I feel like I should start.

Serena: So you sent Ben to prison so that I could go to Constance?
Lily: Well no! Of course not. But after I left the school alerted the authorities and then, I didn't know what I had set in motion until I was contacted by the D.A. and by then it was too late.
Serena: What? Too late to tell the truth? So you just destroy a man's life all so that you can keep up appearances?

B, it's okay. I talked to Juliet. She's not the problem anymore. It's my mom.

Serena: Then you just left me for dead in a motel room. Why, because of Nate? Or Colin?
Juliet: No, you stupid bitch. Because you destroyed my brother's life!

Gossip Girl Quotes

Even Blair Waldorf can not bend DNA to her will.

Dan

Hazel: Do you know what you're doing, Little J?
Jenny: I'm not Little J anymore.