Serena: The photo of me on Gossip Girl. That was you too?
Juliet: Yep. I went out dressed like you and partied like it was 2007.

She wants you all to think she's the perfect host and mother and wife, but the truth is she's a selfish liar who will destroy anyone that gets in her way.

Eric: How are you feeling?
Serena: Betrayed. Thanks.

[calling 911] My name is Serena van der Woodsen. I don't know who I am or how I got here. Please help.

Your daughter wakes up alone, drugged in an empty motel room, and you don't call the cops? You don't ask if she's OK or what happened? You just have her committed? What kind of mother does that?

[to Eric] You're my little brother. You're not enough.

Bouncer: Sorry. Do you have ID?
Serena: I didn't come to rent a car.

Blair: As for your devoted suitors, have you finally decided whom to crush?
Serena: No, and I have feeling for both. I don't want to hurt either. I have a whole new appreciation for Big Love.
Blair: Well. Even in Utah only the men get to have more than one spouse. Which, I've come to realize, is extremely sexist.

Serena: Hey, why are you guys eating? I thought we were going to Sarabeth's.
Eric: Ah, we decided we could spread out better here. There's more room to work.
Serena: On what, your calculus homework?
Eric: Your love life. It's a little something called "Dan vs. Nate". We're here to help.
Elliot: And we brought protractors.

[to Dan] Why do you have mad face?

Blair: It's just your ordinary, run of the mill ex sex, fueled by the most common of aphrodisiacs: mutual loathing and disdain.
Serena: May I remind you that those are both feelings?

Serena: I don't understand. You brought Colin as your date. Are you on a sugar high?
Blair: No. He's your date. Not mine.

Gossip Girl Quotes

Even Blair Waldorf can not bend DNA to her will.

Dan

Hazel: Do you know what you're doing, Little J?
Jenny: I'm not Little J anymore.