Skye: Sweet ride.
Coulson: I earned a little good will from Direct Fury when I got hit right before the battle of New York.
Skye: You took a bullet?
Coulson: "ish".

The name they gave me at the orphanage was Mary Sue Poots

You can't walk away from this. With great power comes.... a ton of weird crap you are not prepared to deal with.

Coulson: I can’t think of a single time when anything alien in human hands ended well.
Skye: Wouldn't mind getting my human hands on Thor. He’s so dreamy.
Coulson: Sure he’s handsome but
May: No he’s dreamy.

Skye: Usually one person doesn't solve the solution, but 100 people with 1% of the solution that will get it done. I think thats beautiful, pieces solving a puzzle.
Ward: You and I see the world differently.

Ward: And the attackers?
Coulson: Invisible.
Skye: Wait Invisible? So cool, but terrible.

Guard: Kids got balls.
Skye: Thanks, but yuck.
Quinn: But do you have what it takes to pull the trigger?
Skye: Nope. [leaps out the window]

Hail Hydra

Ward: She's a groupy, all the hacking into SHIELD, tracking powers. She might as well be one of those sweaty Cosplay characters crowding around Stark tower.
Skye: WHAT?! I would... [whispers] it was just one time.

You and Simmons are so tight, it's like you're psychically linked.

Coulson: Sounds like there's a lot you're willing to forgive.
Daisy: I will never forgive him. He murdered Rosalind just to hurt you. He killed Koenig because of me.
Coulson: He knew once Koenig outed him as HYDRA he'd lose you.
Daisy: And the sad part is, that's when I finally understood him for the first time. The reason Ward kills isn't because he feels nothing. It's because he feels too much.

Coulson: Skye, hey? Skye are you okay? Skye?
Daisy: It's Daisy.
Coulson: What?
Bobbi: It's Daisy now sir. You're really having a hard time with this huh?
Coulson: Damn it, yeah.

Agents of S.H.I.E.L.D. Quotes

Kasius: Yo-Yo Rodriguez? How peculiar.
Yo-Yo: Says the space mime!

Sousa: Hey, what are you doing up?
Daisy: Why do you care?
Sousa: Because you don't.