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Watson: Do you close yourself off to people, deny yourself things that might bring you pleasure? Not because it makes you a better investigator but because it's some sort of penance?
Watson: For what happened in London? Being addicted? I don't know, it just occurred to me that it might something someone would do and not even know it.
Sherlock: You always know it, Watson. If you didn't, it wouldn't be penance.