Daisy: You are not cursed. You are not some horrible thing. I know, because you taught me that I wasn't. You convinced me that I had a purpose. That maybe my life wasn't over, but just getting somewhere. Please let me do the same for you.
Lincoln: You're wasting your time caring about me.
Daisy: I can't help it.

Coulson: Where are you taking the victims?
Rosalind: That's classified. Oh, it's not fun when it's you, right? Can't believe I just said that to the Director of S.H.I.E.L.D.
Coulson: You know, I'm really not feeling the spirit of cooperation here.

Simmons: I know you're looking for signs of PTSD, but I assure you I'm fine.
Garner: You've been through something pretty extreme. There will be after-effects, and that's okay. It's okay to struggle.

Coulson: Mr. Frye we can help you, but you have to trust me. This Lash is not some angel of mercy.
Frye: No, he's no angel. He's just a guy trying to do the right thing.

This is Doctor Jemma Simmons updating the file on the monolith Fitz and I have been studying. I now know that it is an alternating matter transportation device. A portal. Quite remarkable really, I've been transported to an unknown planet. In a different solar system.

Simmons

Will: If you're not with NASA, how did you get into the monolith?
Jemma: It's not with NASA anymore. It's with S.H.I.E.L.D. They've had it for quite some time. I'm not sure how or why.
Will: That's real, S.H.I.E.L.D?
Jemma: It was, I was recruited right out of the academy.
Will: I was a test pilot for the Air Force, recruited by NASA. Now here I am.
Jemma: Here we are. At least you volunteered.
Will: Yeah.

Jemma: You were right, there's no hope on this planet.
Will: That's what I used to think. Then you showed up.

Everyone always said we could read each others minds, Fitz. So, I really need you to read mine right now. I'm alive, but I'm terribly alone and afraid. So I really need you to come and get me, okay? I know you won't give up, so I won't either.

Jemma

Jemma: Perhaps it's best if we start over since we're going to be working together.
Will: Working together? On what?
Jemma: On getting home.
Will: There's no getting home. Sooner you accept that the better. Survival's all that matters.
Jemma: I will not accept that. There's always hope.

Will: That thing has been killing everyone that's come through here for centuries.
Jemma: How long have people known about the monolith? And why keep sending people when there's no way back? It's as if they're being sacrificed.

I don't know what happened to him. If he's alive or dead. But I never would have survived without him.

Jemma

Hill: What does S.H.I.E.L.D. stand for Agent Ward?
Ward: Strategic Homeland Intervention, Enforcement and Logistics Division.
Hill: And what does that mean to you?
Ward: That someone really wanted our initials to spell SHIELD.

Agents of S.H.I.E.L.D. Quotes

Kasius: Yo-Yo Rodriguez? How peculiar.
Yo-Yo: Says the space mime!

Sousa: Hey, what are you doing up?
Daisy: Why do you care?
Sousa: Because you don't.