[to Mer] "Oh, nice try with the fancy words. He needs an enema, and the answer is no."

CRISTINA

• Permalink: Oh, nice try with the fancy words. He needs an enema, and the ...
• Added: July 16, 2006

CRISTINA: "What the hell is this?"
PRESTON: "It's a key."
CRISTINA: "Why?"
PRESTON: "Why is it a key? Are we feeling existential this morning?"
CRISTINA: "Well, if the key turns in a lock, and no one asked for the key or even wanted the key, does it make a sound?"

• Permalink: What the hell is this? It's a key. Why? Why is it a key? ...
• Added: July 16, 2006

ADDISON: "Dory, this is Dr. Shepherd. He's our head of neurosurgery."
DEREK: "Hi."
DORY: "Oh, another Dr. Shepherd."
ADDISON: "He's my husband, actually."
DORY: "Seriously?"
DEREK: "Mmm-hmm."
DORY: "Wow. Look at you two. Everybody must hate you.
ADDISON: "You have no idea."

• Permalink: Dory, this is Dr. Shepherd. He's our head of neurosurgery. Hi...
• Added: July 16, 2006

[to Izzie] "Don't even pretend that you haven't been judging me since the minute we met."

DORY

• Permalink: Don't even pretend that you haven't been judging me since the ...
• Added: July 16, 2006

[to Steve] "There'll be lots of labs, lots of needles, lots of painful procedures. Procedures which might make you wish you never had a penis. You sure you don't want to change your story?"

MIRANDA

• Permalink: There'll be lots of labs, lots of needles, lots of painful pro...
• Added: July 16, 2006

[to Mer & Cristina] "Hey! Don't make me chase you down. I'm growing a person here!"

MIRANDA

• Permalink: Hey! Don't make me chase you down. I'm growing a person here!
• Added: July 16, 2006

"It's not my fault you broke the guy's penis."

CRISTINA

• Permalink: It's not my fault you broke the guy's penis.
• Added: July 16, 2006

IZZIE: [about Alex] "He said it's never happened before."
GEORGE: "That's what we all say. I mean they. That's what they all say."

• Permalink: He said it's never happened before. That's what we all say. ...
• Added: July 16, 2006

MEREDITH: "What are you doing here... um... Steve?"
STEVE: "I'm having a little problem."
CRISTINA: "Steve, Steve?"
STEVE: "Actually, I'm having a big problem."
MEREDITH: What?
CRISTINA: [staring] "Steve! Hi, Cristina."
STEVE: [to Mer] "Ever since you...and I... um... it won't go away."
MEREDITH: [sees her staring] "Cristina!"
CRISTINA: "What? It's right there, looking at me! There are so many things I could say right now. Champ!"

• Permalink: What are you doing here... um... Steve? I'm having a little p...
• Added: July 16, 2006

CRISTINA: [holds up key]
MEREDITH: "Burke keyed you?"
CRISTINA: "I got freaking keyed before coffee."
MEREDITH: "What is wrong with them?"
CRISTINA: "They're like these 1950s debutantes, one dance and there's a shotgun to your head."

• Permalink: Burke keyed you? I got freaking keyed before coffee. Wha...
• Added: July 16, 2006

[to Cristina] "They always look so sad when I kick them out. Seriously, why do guys not understand that when you pick them up in a bar and take them home for sex, that there are no picket fences or kids in your future?"

MEREDITH

• Permalink: They always look so sad when I kick them out. Seriously, why d...
• Added: July 16, 2006

[to pregnant patient expecting quints] "Guess when you take those fertility pills, you should read the fine print, huh?"

IZZIE

• Permalink: Guess when you take those fertility pills, you should read the...
• Added: July 16, 2006