Open the landing bay doors, shuttle craft approaching.

Leonard

Howard: You gotta like this. The girlfriend, the ex-girlfriend bonding over your rooty-tooty stinky booty.
Leonard: Kill me.
Sheldon: It wouldn't help. The human body is capable of being flatulent for hours after death.

Bernadette: The thesis committee accepted my doctoral dissertation. I'm getting my Ph.D!!
(the other congratulate her)
Penny: Wow! So that means that....(points around the table to all the Ph.D's) You're a doctor, you're a doctor, you're a doctor, YOU'RE a doctor, and Howard....you know a lot of doctors!!

Howard: You gotta like this: the girlfriend.....the ex-girlfriend, bonding over your rooty-tooty stinky booty?
(all but Leonard laugh)
Leonard: Kill me!
Sheldon: It wouldn't help. The human body is capable of being flatulent for hours after death.

Rotting Zombie ... Sheldon's new Facebook photo!

Raj

Try not to ogle my caboose as I walk away.

Amy

(To a box of expensive shoes she's about to take back)
Penny: I'm sorry, shoes, but you have to go back.
Shoebox (Penny): But, Penny, we love you.
Penny: I love you, too, but you cost more than my rent.
Shoebox (Penny): But Penny, you look so good in us.
Penny: (To Amy) Damn it, the shoes are right!

Priya: They dressed up in leotards and goggles and called themselves the New Delhi Power Rangers.
Penny: How old were they?
Priya: Not as old as you'd want them to be.

Howard's mother had a heart attack because I have sex with him and she can't!

Bernadette

Whereas Jewish mothers take a casual la-dee-dah approach to their sons.

Wolowitz

You brought a Catholic girl home to you mother? Why don't I write you a prescription for Xanax.

Doctor

Leonard: Does your family have a history of heart disease?
Wolowitz: My family is the history of heart disease. There's a cave painting in France of one of my ancestors doing this. [mimicks heart attack]

The Big Bang Theory Season 4 Quotes

You have broad hips and a certain corn-fed vigor. Is your womb available for rental?

Sheldon

At best, it's a modest leap forward from the technology that gave us Country Bear Jamboree.

Sheldon