Homer Simpson, voiced by Dan Castellaneta, is the patriarch of The Simpsons and is definitely the main character.  Homer is an overweight, slob and a terrible father, but genuinely tries hard.

Homer previously had a job as safety inspector at Mr. Burns' Nuclear Power Plant, but good luck finding out what he's been doing for a living the last few years.

Homer Simpson Quotes

And I'm 69 because people always laugh when you say "69." Hehe, no one knows why.

Homer

Bart: Hey, Mom. Did you save Dad's love letters?
Marge: Of course I saved them. Well actually, there's only one. It's more of a love postcard from some brewery he visited.
Homer: Maybe it's the beer talking, Marge. But you've got a butt that won't quit. They've got these big chewy pretzels here (undecipherable slurring) five dollars?! Get outta here!
Bart: Wow, the side of Dad I've never seen.

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The Simpsons Quotes

And I'm 69 because people always laugh when you say "69." Hehe, no one knows why.

Homer

Bart: Hey, Mom. Did you save Dad's love letters?
Marge: Of course I saved them. Well actually, there's only one. It's more of a love postcard from some brewery he visited.
Homer: Maybe it's the beer talking, Marge. But you've got a butt that won't quit. They've got these big chewy pretzels here (undecipherable slurring) five dollars?! Get outta here!
Bart: Wow, the side of Dad I've never seen.