I was put in charge of the T.A.H.I.T.I. project so those people are my responsibility. If going back in this machine saves even one life, then it's worth the risk.

Simmons: She had GH.325 in her blood.
Coulson: A T.A.H.I.T.I. patient?
Simmons: Whoever killed her also had GH.325 in their blood.

Skye: You two don't have a single thing in common unless you have some Enya albums you've been hiding.
Coulson: No, nothing in common at all.
Skye: I take that back.

May gave specific instructions, you go on a date with a crazy wall I have to chaperone.

Skye

Senator Ward: The American people are looking for a simple enemy Mr. Coulson. It's what makes them feel safe.
Coulson: And how do you think they'd feel if they knew your brother was HYDRA? That's an awfully complicated idea to grasp. Especially in an election year.
Senator Ward: Are you threatening me Mr. Coulson?
Coulson: No, I'm telling you I have your brother in my basement.

Coulson: I don't know how else to explain it but it needs to be carved.
Skye: Does it just appear in your mind like some sort of vision?
Coulson: No, it just kinda happens. Which is really frustrating because no matter how much I carve it still means nothing to me. I don't even have a theory.
Skye: I do. It's a map.

Skye: Hold on are you saying that I am an alien?
Coulson: It's a theory.
Skye: No a theory is what scientists use to prove things in nature. This is you telling me that I might be an alien. That is not something you just say like it's no big deal.
Coulson: I was trying not to rattle you.
Skye: Guess what? Epic fail.

Laser grids. Why is it always laser grids?

Fitz: Is there anything more?
Coulson: That I'm keeping from you? Yeah I'm Director, there's a hell of a lot more. But there is one other thing you should know. Simmons is on an assignment. That's why she hasn't been in contact. That's why she left.

Undercover is all about the relationships you make. If you're going to move up in HYDRA you need to make friends.

Maria Hill: Get your people we have to move.
Coulson: We?

If I come out, will you shoot me? 'Cause then I won't come out.

Agents of S.H.I.E.L.D. Quotes

Kasius: Yo-Yo Rodriguez? How peculiar.
Yo-Yo: Says the space mime!

Sousa: Hey, what are you doing up?
Daisy: Why do you care?
Sousa: Because you don't.