Sam: We landed in some dimension where you're called Jensen Ackles and I'm something called a Jared Padalecki.
Dean: So, what? Now you're Polish?

Dude, they put freakin make up on us. Those bastards.

I'm not wearing any makeup. Oh crap. I'm a painted whore.

Hey, you leave my baby alone! She's got nothing to do with this!

Dean: Hey, maybe we'll have a Snooki sighting.
Sam: What's a Snooki?
Dean: That's a good question.

We've been Parent Trapped.

I don't like the way Kim Cattrall is looking at me.

So, what? We've got a bunch of killer dolls? Like Chucky?

Sam: Wait. That anatomy dummy you were molesting at the lab.
Dean: Excuse me?
Sam: What if that's what this is about?
Dean: What exactly are you accusing me of?

Dean: Be my valentine?
Sam: Dude, we're working. Put it back.
Dean: Have a heart.

Sam: So, Mel Gibson really took a turn this past year, huh?
Dean: Or he's possessed. Seriously. Think about it.

My Spidey senses are tingling.

Supernatural Quotes

Dean: Where am I going?
Sam: Dean, it's Valentine Day. Your favorite holiday, remember? I mean, what do you always call it - uh, Unattached Drifter Christmas?

You betrayed me? No one in the history of torture's been tortured with torture like the torture you'll be tortured with.

Crowley