House: But, when you're 4th down, 100 to go, in the snow, you don't call a running play up the middle. Unless you're the Jets.
Dr. Cameron: I hate sports metaphors.

House: I am selling my soul.
Dr. Wilson: Just a little piece. And you are getting something in return.
House: I said I was selling it. I didn't say I was giving it away. That would be immoral and stupid.

You have kids! How novel! That changes everything. So if Mommy has heartburn, one of them might catch on fire.

Men are pigs - you have nothing to worry about. They will pretty much have sex with anyone - young, old, heavy, thin, complete strangers, relatives.

Dr. Cameron: I apologize if it looked like we weren't devoting our full attention to your daughter, but I assure you that we...
Mrs. Simms: Oh please, save your pathetic insincerity for your boyfriend.
House: You're wrong! She is in fact pathetically sincere.

House: Figures you'd try and come up with a solution where no one gets hurt. The problem is, the world doesn't work that way just 'cause you want it to.
Dr. Cameron: Figures you'd stall and refuse to deal with the issue. Problem is, the world doesn't go away just because you want it to.

House: Somebody told Vogler that I lied to the transplant committee.
Dr. Foreman: You think I did?
House: You're too careful. You wouldn't jump ship unless you knew what was in the water.
Dr. Foreman: Stop, you're embarrassing me.

Dr. Wilson: Seriously man, have you ever actually driven an automobile before? There are four gears, you know.
House: The '66 came with a shut-up button.

House: Oh, stop hiding! I'm asking you if you want to live or die, you can't even say that!
Carly: What do you want me to do? Cry?
House: Yes! I want you to tell me that your life is important to you, because I don't know! Because that's what's on the table right now: your life.

Dr. Wilson: Oh, this is where I give you advice and pretend you're going to listen to it. I like this part. Did Rowan ask you not to tell?
House: I promised I wouldn't. My fingers were crossed, so I'm wide open.
Dr. Wilson: I was wrong - this is the musing out loud part. Do I actually need to be here?

Dr. Wilson: On the other hand, there is the 'do unto others' thingy?
House: Then I should definitely tell him. I'd want to know.
Dr. Wilson: You want to know everything. There's also the 'keeping your promises' thingy.
House: You never run out of thingies.

(talking to a Vicodin pill) There you are. Were you scared? It's okay, you're home now. (swallows it)

House Quotes

Dr. Cameron: House doesn't believe in pretense. Figures life's too short and too painful. So he just says that he thinks.
Dr. Foreman: "I say what I think" is just another way of saying "I'm an assho"...

(about House) The son of a bitch is the best doctor we have.

Dr. Cuddy