....I volunteered for the premature ejaculation project. I mean, it's not like either one of us has heart disease.

Bernadette to Howard

Howard: You gotta like this. The girlfriend, the ex-girlfriend bonding over your rooty-tooty stinky booty.
Leonard: Kill me.
Sheldon: It wouldn't help. The human body is capable of being flatulent for hours after death.

Howard: You gotta like this: the girlfriend.....the ex-girlfriend, bonding over your rooty-tooty stinky booty?
(all but Leonard laugh)
Leonard: Kill me!
Sheldon: It wouldn't help. The human body is capable of being flatulent for hours after death.

Whereas Jewish mothers take a casual la-dee-dah approach to their sons.

Leonard: Does your family have a history of heart disease?
Wolowitz: My family is the history of heart disease. There's a cave painting in France of one of my ancestors doing this. [mimicks heart attack]

Have you told your parents you're dating this short glass of skim milk?

Her freakishly small hands make anything look big. That's one of the reasons I love her.

Believe in magic, you Muggle!

That crazy bastard is looking at quirky in the rear view mirror.

I think it's like Beetlejuice. We said his name too many times.

Leonard: Still arguing which is the best CSI?
Howard: We agreed they all have their merits.

Howard: I'm not having this conversation with you Ma!
Howard's Ma: God forbid you get one of those new fancy sex diseases!

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?