Sheldon: Count me out.
Leonard: What? ...why?
Sheldon: You want me to use my intelligence in a tawdry competition. Would you ask Picasso to play Pictionary? Would you ask Noah Webster to play Boggle? Would you ask Jacques Cousteau to play Go Fish?

Leslie: Wait, you're going up against Sheldon Cooper?
Leonard: Yeah.
Leslie: That arrogant, misogynistic East Texas doorknob that told me I should abandon my work with high-energy particles for laundry and childbearing?

Leonard: Sheldon, you have to let somebody else answer.
Sheldon: Why?
Penny: Because it's polite.
Sheldon: What do manners have to do with it? This is war. Were the Romans polite when they salted the ground of Carthage to make sure nothing would ever grow again?

Sheldon: I've designed the perfect uniforms for our team. The colors are based on Star Trek: The Original Series; the three of you will wear support red, and I will wear command gold.
Leonard: Why do they say, "AA"?
Sheldon: Army Ants.
Leonard: Isn't that confusing? AA might mean something else to certain people.
Sheldon: Why would a Physics Bowl team be called Anodized Aluminum?

Sheldon: Point of order. I move that any vote on team names must be unanimous. No man should be forced to emblazon his chest with a Bengal tiger when common sense dictates it should be an army ant.
Leonard: Will the gentleman of the great state of denial yield for a question?
Sheldon: I will yield.
Leonard: After we go through the exercise of an annoying series of votes, all of witch the gentleman will lose, does he then intend to threaten to quit if he does not get his way?
Sheldon: He does!
Leonard: I move we are the Army Ants

Leonard: Check it out. I got you a Batman cookie jar.
Sheldon: Ohhh, neat, what is the occasion?
Leonard: Well, you are a friend, and you like Batman and cookies, and you are off the team

Wolowitz: Oh, more details about the new Star Trek film. There's going to be a scene depicting Spock's birth.
Raj: I'd be more interested in a scene depicting Spock's conception.
Sheldon: Oh, please. For Vulcans, mating—or if you will, pon farr—it's an extremely private matter.
Leonard: Still, I'd like to know the details. His mother was human; his father was Vulcan. They couldn't just conceive.
Wolowitz: Maybe they had to go to a clinic. Can you imagine Spock's dad in a little room with a copy of Pointy Ears and Shapely Rears?

Leonard: You always knew that someday someone would come along who was younger and smarter.
Sheldon: Yes, but I assumed I would have been dead hundreds of years and that there'd be an asterisk next to his name because he'd be a cyborg

Raj [referring to Dennis Kim]: Do you know what he did? He watched me work for ten minutes and then started to design a simple piece of software that could replace me.
Leonard: Is that even possible?
Raj: As it turns out, yes

Sheldon: What happens if you use argon lasers instead of helium-neon?
Leonard: It would blow up!
Sheldon: Are you sure?
Leonard: Pretty sure...
Sheldon: Pretty sure? It's not very scientific. Is this how you normally work? Just hunches and guesses and stuff?

Raj: We need a social catalyst.
Leonard: Like what? We can't get 15-year-old girls drunk.
Wolowitz: Or can we...!?

Sheldon: Here's the problem with teleportation.
Leonard: Lay it on me.
Sheldon: Assuming a device could be invented, which would identify the quantum state of matter of an individual in one location and transmit that pattern to a distant location for reassembly. You would not have actually transported the individual, you would have destroyed him in one location and recreated him in another.
Leonard: How about that.
Sheldon: Personally, I would never use a transporter because the original Sheldon would have to be dissintegrated in order to create a new Sheldon.
Leonard: Would the new Sheldon be in any way an improvement on the old Sheldon?
Sheldon: No, he would be exactly the same.
Leonard: That is a problem

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?